9-Methylacridine was identified as a generally effective ligand to promote a Pd(II)-catalyzed C(sp(3))-H and C(sp(2))-H alkylation of simple amides with various alkyl iodides. This alkylation reaction was applied to the preparation of unnatural amino acids and geometrically controlled tri- and tetrasubstituted acrylic acids.

The catalytic activities of SBA-15 aluminosilica meso/macroporous monoliths (Si/Al = 72) and mesoporous powders (Si/Al = 70) have been investigated using batch Friedel–Crafts alkylation of single-ring aromatic compounds, including toluene, ethylbenzene, cumene, and styrene, with benzyl alcohol. The toluene alkylation activities of the meso/macroporous monolith catalysts were compared with nanop...

Reductive catalytic fractionation of biomass has recently emerged as a powerful lignin extraction and depolymerization method to produce monomeric aromatic oxygenates in high yields. Here, bifunctional molybdenum-based polyoxometalates supported on titania (POM/TiO2 ) are shown to promote tandem hydrodeoxygenation (HDO) and alkylation reactions, converting lignin-derived oxygenated aromatics in...

The alkylation of a variety ketones using 1° or 2° alcohols under hydrogen borrowing catalysis is described. Initial research focused on the ?-alkylation cyclopropyl with higher (i.e. larger than MeOH), leading to formation ?-branched products. Our search for additional substrates which explore this chemistry led us discover that di- ortho -substituted aryl were also privileged scaffolds, Ph? (...

Evaluation of a new proton sponge, bis-1,1,8,8-(tetramethylguanidino)naphtalene (TMGN), in substituted phenols O-alkylation by methyl iodide in DMF has been studied. Kinetic measurements were performed in N,N-dimethylformamide-d7 and followed by H NMR using stoichiometric amounts of reagents. Plot of the results shows that the reaction follows an almost perfect second order rate law. However th...

Tandem hydrodechlorination/Friedel–Crafts alkylation of poly(vinyl chloride) (PVC) is achieved using silylium ion catalysts to prepare new styrenic copolymers polyethylene.

a series of n-substituted-2,4-thiazolidinedione derivatives (tzds) were prepared via n-alkylation of 2,4-tzd at position 3 using substituted benzyl halides. synthesized n-substituted-2,4-tzd was then substituted at position 5 with substituted aromatic aldehyde according to knoevenagel condensation method. structures of the compounds were elucidated using various spectral techniques viz. ir, 1hn...

Key words alkylation - nitronates nitroalkanes α-tertiary amines ‘ene’-reductase (ERED) photoredox catalysis

The process of sulfuric alkylation isobutane with olefins is considered. model 
 the was simulated using Aspen HYSYS package

Abstract Borrowing hydrogen (BH) reactions are very useful for the sustainable synthesis of C−C and C−N bonds. They generally operate with transition metal‐based catalysts along stoichiometric/catalytic amounts added base. Here we report that two catalytic transformations, carried out BH methodology, i. e. N ‐alkylation amines alcohols β‐alkylation secondary primary alcohols, can be performed e...