نتایج جستجو برای: alkhumra haemorrhagic fever virus
تعداد نتایج: 478138 فیلتر نتایج به سال:
The complete nucleotide sequences of the small (S) and medium (M) segments of three independent strains of Crimean-Congo haemorrhagic fever (CCHF) virus isolated in Uzbekistan, Iraq and Pakistan have been determined. Partial S and M segment sequences from two additional strains and partial large segment sequences from five strains of CCHF virus have also been obtained. These data have been comp...
Dengue has become a serious public health problem in India. More than 50 outbreaks of dengue have been reported in different parts of the country1,2. In India Aedes aegypti Linn (Diptera: Culicidae) is a principal vector of dengue and dengue haemorrhagic fever (DHF)3. Dengue virus has also been recently detected in Ae. albopictus Skuse4. Ae. aegypti has a widespread distribution in many towns a...
The appearance of novel pathogens of humans with epidemic potential and high mortality rates have threatened global health security for centuries. Over the past few decades new zoonotic infectious diseases of humans caused by pathogens arising from animal reservoirs have included West Nile virus, Yellow fever virus, Ebola virus, Nipah virus, Lassa Fever virus, Hanta virus, Dengue fever virus, R...
Several human infections have emerged in the last three decades, most of them are attributed to wildlife origin. Two third emerging zoonotic viruses. Emerging and re-emerging fatal viral diseases like Nipah virus disease, Hendra Virus Severe Acute Respiratory Syndrome, Middle East Ebola Marburg haemorrhagic fever been witnessed recently, causative agents which associated with bats. Ecology bats...
Mild hepatic dysfunction in dengue haemorrhagic fever is not unusual. However, acute liver failure (ALF) is rare. When present, its management according to most current guidelines is supportive and carries a poor prognosis. We present a patient with dengue haemorrhagic fever complicated acute liver failure and hepatic encephalopathy who was successfully treated with N-Acetylcysteine (NAC) leadi...
Cardiac rhythm abnormalities, including ventricular arrhythmia, atrial fibrillation and atrioventricular block, have been observed during the acute stage of dengue haemorrhagic fever. Atrioventricular or complete heart block can be fatal and may require a temporary pacemaker. We report a ten-year-old girl who presented with dengue haemorrhagic fever with sinoatrial block and atrioventricular di...
In recent years, the demand for new antiviral strategies has increased markedly. There are many contributing factors to this increased demand, including the ever-increasing prevalence of chronic viral infections such as HIV and hepatitis B and C, and the emergence of new viruses such as the SARS coronavirus. The potential danger of haemorrhagic fever viruses and eradicated viruses such as vario...
Ebolavirus, a member of the Filoviridae family of negative-sense RNA viruses, causes severe haemorrhagic fever leading up to 90% lethality. Ebolavirus matrix protein VP40 is involved in the virus assembly and budding process. The RNA binding pocket of VP40 is considered as the drug target site for structure based drug design. High Throughput Virtual Screening and molecular docking studies were ...
BACKGROUND Predicting when and where pathogens will emerge is difficult, yet, as shown by the recent Ebola and Zika epidemics, effective and timely responses are key. It is therefore crucial to transition from reactive to proactive responses for these pathogens. To better identify priorities for outbreak mitigation and prevention, we developed a cohesive framework combining disparate methods an...
Ebola zoonotic RNA filovirus represents human most virulent and lethal pathogens, which induces acute hemorrhagic fever and death within few days in a range of 60-90% of symptomatic individuals. Last outbreak in 2014 in West Africa caused panic that Ebola epidemic can be spread to other continents. Number of deaths in late December reached almost 8,000 individuals out of more than 20,000 sympto...
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