نتایج جستجو برای: alkaline serine proteases

تعداد نتایج: 93954  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1996
Q D Dang E Di Cera

Residue 225 in serine proteases is typically Pro or Tyr and specifies an important and unanticipated functional aspect of this class of enzymes. Proteases with Y225, like thrombin, are involved in highly specialized functions like blood coagulation and complement that are exclusively found in vertebrates. In these proteases, the catalytic activity is enhanced allosterically by Na+ binding. Prot...

Journal: :Journal of Biological Chemistry 1931

Journal: :Journal of Biological Chemistry 2004

Journal: :Frontiers in Cellular and Infection Microbiology 2021

Journal: :Proceedings of the National Academy of Sciences 1971

2008
Hideo Baba Atsushi Irie Hidetomo Kobayashi Keinosuke Okamoto Hidetoshi Nitta Takahisa Imamura Yoshihiro Wada

2014
Nicolas Faller Ivan Gautschi Laurent Schild

Membrane-bound serine proteases play important roles in different biological processes. Their regulation by endogenous inhibitors is poorly understood. A Y163C mutation in the SPINT2 gene encoding the serine protease inhibitor Hepatocyte Growth Factor Inhibitor HAI-2 is associated with a congenital sodium diarrhea. The functional consequences of this mutation on HAI-2 activity and its physiolog...

Journal: :Acta Crystallographica Section A Foundations of Crystallography 2010

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید