The development of bio-resorbable implant materials is rapidly going on. Sterilization of those materials is inevitable to assure the hygienic requirements for critical medical devices according to the medical device directive (MDD, 93/42/EG). Biopolymer-containing biomaterials are often highly sensitive towards classical sterilization procedures like steam, ethylene oxide treatment or gamma ir...

The current study describes an approach for creating covalently bonded complexes of sodium caseinate (NaCas) and propylene glycol alginate (PGA) without using a cross-linking agent. principle is based on transacylation reaction between the esterified carboxylic groups PGA amino NaCas during pH shift from alkaline (pH 12.0) to neutral condition 7.0). increased molecule weight at higher amount ob...

We report herein the development of a self-assembly method to rapidly produce cell-like, filamentous microcapsules (MCs) that have high surface area and encapsulate liquids or gels. The fibrous surfaces and shell walls of the MCs can be biologically functionalized using bioactive peptide amphiphiles (PAs), and the cores can harbor biopolymers, proteins, and other macromolecules. This novel meth...

Alginate denotes a group of industrially important 1-4-linked biopolymers composed of the C-5-epimers β-D-mannuronic acid (M) and α-L-guluronic acid (G). The polysaccharide is manufactured from brown algae where it constitutes the main structural cell wall polymer. The physical properties of a given alginate molecule, e.g., gel-strength, water-binding capacity, viscosity and biocompatibility, a...

Two printing methods, extrusion and inkjet, are used to deposit tracks of PEDOT/PSS conducting polymer onto biopolymer films with a view to prepare implantable tissue mimics containing electronic devices. Extruded tracks offer lower printing resolution, but better electrical characteristics compared to inkjet printed tracks. The biopolymer–ink interaction results in narrower printed tracks comp...

The hypolipidemic effect of an exo-biopolymer produced from a submerged mycelial culture of Hericium erinaceus was investigated in dietary-induced hyperlipidemic rats. Hypolipidemic effects were proportionally increased with the increasing concentration of the exo-biopolymer for oral administration. The exo-biopolymer, at the dose of 200 mg/kg body weight, substantially reduced the plasma total...

Four hydrophilic polymers in the form of beads - chitosan, alginate, alginate/polyvinyl alcohol (PVA), and chitosan-coated alginate - were used as supports for lipase immobilisation. Hydrogel beads were characterised by bead-size-distribution estimation, surface morphology studies, and polymer interactions assessment. Matrix performances - loading efficiency, immobilisation yield, enzyme activi...

The purpose of this study was to develop the pathway of silk fibroin (SF) biopolymer surface induced cell membrane protein activation. Fibroblasts were used as an experimental model to evaluate the responses of cellular proteins induced by biopolymer material using a mass spectrometry-based profiling system. The surface was covered by multiwalled carbon nanotubes (CNTs) and SF to increase the s...

We describe a method for creating alginate hydrogels with adjustable degradation rates that can be used as scaffolds for stem cells. Alginate hydrogels have been widely tested as three-dimensional constructs for cell culture, cell carriers for implantation, and in tissue regeneration applications; however, alginate hydrogel implants can take months to disappear from implantation sites because m...

In this review, a historical perspective, functional and application trends of natural polymers used to the development edible food packaging were presented discussed. Polysaccharides proteins, i.e., alginate; carrageenan; chitosan; starch; pea protein, considered. These are important materials obtained from renewable plant, algae animal sources, as well agroindustrial residues. Historically, s...