quaternary structure of G protein-coupled receptors. FEBS J. 272:2914–2925 Stein C, Schafer M,Machelska H (2003) Attacking pain at its source: new perspectives on opioids. Nat Med 9:1003–1008 Waldhoer M, Bartlett SE, Whistler JL (2004) Opioid receptors. Annu Rev Biochem 73:953–990 Williams JT, Christie MJ, Manzoni O (2001) Cellular and synaptic adaptations mediating opioid dependence. Physiol R...