INTRODUCTION .................................................................. Methods. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Results. ....................................................................... Treated rats. ............................................................... Untreated...

[We gladly avail ourselves of an opportunity afforded by the kindness of Mr. Turnbull of laying before our readers a translation of Salvatori's celebrated dissertation on Drunkenness?a dissertation little kuown in this country from the great scarcity and difficulty of access of the volume in which it originally appeared. This essay is of rare interest to the medical scholar, not only because in...

BACKGROUND Prevention of alcohol, drug and tobacco misuse by young people is a key public health priority. There is a need to develop the evidence base through rigorous evaluations of innovative approaches to substance misuse prevention. The Strengthening Families Programme 10-14 is a universal family-based alcohol, drugs and tobacco prevention programme, which has achieved promising results in...

We study the effects of the presence of contrarians in an agent-based model of competing populations. Contrarians are common in societies. These contrarians are agents who deliberately prefer to hold an opinion that is contrary to the prevailing idea of the commons or normal agents. Contrarians are introduced within the context of the minority game (MG), which is a binary model for an evolving ...