Albinism has a profound effect on visual development and visual function. Pharmacologically significant alterations of the two most important chloride-transporters--KCC2 (outward transporter) and NKCC1 (inward transporter)--functions were found in albino visual cortex neurons, comprising a higher NKCC1 and a lower KCC2 action. In this study, we compare the early postnatal development of the rev...

In all albino mammals studied the central retina is underdeveloped and there is a rod deficit. Central ganglion cell density is approximately 25% below normal. This is not seen in birds, which have a come dominated retina. Here we examine the ganglion cell layer in a cone rich mammal, the squirrel Sciurus carolinensis leucotis. Central cell densities were only < 5% lower in the albinos than in ...

For over two decades H. VON EULER (3) and his coworkers have studied the relationship of catalase to chlorophyll. In their work they utilized various chlorophyll defective plants including genetic albinos, variegated, chlorotic and etiolated plants. In general, they found a parallelism between chlorophyll content and catalase activity. NAKAMURA (11) working with a number of higher and lower for...

Introdução: Vários autores descrevem diferentes modelos de aterosclerose experimental, muitos deles, sem descrições claras dos métodos e na maioria das vezes utilizando colesterol puro misturado a ração, o que torna experimento mais caro complexo. Objetivo: objetivando padronização um modelo dieta experimental simples, facilmente reprodutível baixo custo, testamos três para verificar qual desta...

Objective: The aim of this study was to investigate the toxicity; analgesic and anti-pyretic properties of standardized HA methanolic extract (HAMeOH) in vivo. Methods: The acute toxicity study was performed on rats while adopting the OECD-420 Guidelines (fixed dose procedure). Assessment of analgesic activity was performed in rats with two analgesic models. One was acetic acid induced writhing...

L'albinisme regroupe un ensemble d'affections héréditaires liées à une anomalie de biosynthèse de la mélanine secondaire à un déficit variable en tyrosinase, enzyme impliquée dans la synthèse de ce pigment. La mélanine est élaborée dans des cellules spécialisées de la peau, des cheveux, de l'épithélium pigmenté de la rétine et au niveau de l'iris. L'examen à la lampe à fente d'un sujet albinos ...

Human albinism is characterized by a disturbance of the chiasmatic projection system leading to predominant representation of just one eye in the contralateral hemisphere. Patients show congenital nystagmus without perceiving oscillopsia. The purpose of the present study was to demonstrate the consequences of atypical chiasmatic crossing with monocular visual stimulation using functional magnet...

El presente trabajo de investigación tiene como evaluar el efecto fisopatológico la hidrargiria en estructuras sistémicas murinos, lo cual se realizó laboratorio Fisiología y Ciencias Naturales Facultad Biológicas. Se utilizaron 12 ratones albinos Mus musculus, variedad Balb/c, donde realizaron tratamientos tres grupos experimentales uno control. Cabe mencionar que machos hembras, edad promedio...

Background: The human thyroid gland is located in the front of neck. It consists two lobes. lobes are joined with each other by isthmus. mood stabilizer Lithium Caronate has deleterious effects on gland. Aim: To observe and report data harmful effect weight changes Methods: Sixteen rats were selected for this experimental study. rodents divided into groups. Group A comprised eight animals which...