نتایج جستجو برای: akbari array saa

تعداد نتایج: 135800  

Journal: :Drug metabolism and disposition: the biological fate of chemicals 2014
Hui Xu Yanli Li Xin Che Hongcui Tian Huaying Fan Ke Liu

This study investigated the metabolism of salvianolic acid A (SAA) both in vivo and in vitro. Liquid chromatography-mass spectrometry analysis of drug-containing rat bile samples and bile samples hydrolyzed by glucuronidase revealed a series of methylated conjugates of SAA and its glucuronides, as well as the predominance of the methylation pathway of SAA in rats. For the first time, four major...

Journal: :The Journal of biological chemistry 1982
J S Hoffman E P Benditt

Bacterial endotoxin is a potent inducer of the serum amyloid protein (apo-SAA), a high density lipoprotein (HDL) apoprotein. In a study of the induction of apo-SAA and the structure of apo-SAA-rich lipoprotein particles in mice, we have observed that, following intraperitoneal administration of Salmonella typhosa lipopolysaccharide (50 micrograms), plasma apo-SAA levels rose from base-line leve...

Journal: :The Journal of Experimental Medicine 1976
K P McAdam J D Sipe

The serum precursor SAA of the secondary amyloid protein AA has been detected by solid-phase radioimmunoassay as a normal serum alpha-globulin of mol wt 160,000, which dissociates to a more stable 12,500 dalton moiety on treatment with formic acid. In 12 strains of mice, including T-cell-deficient nude mice, treated with the amyloid-inducing agents lipopolysaccharide (LPS) or casein, SAA behave...

Journal: Journal of Nuts 2019

The pistachio green stink-bug, Brachynema germari Kolenati (Hem.: Pentatomidae), is an important pest of pistachio in Iran. In this research, the effects of four commercial pistachio cultivars that are commonly grown in Iran including Kaleghochi, Ahmadaghaii, Ohadi and Akbari were evaluated on the biology (developmental time, mortality rate, longevity) and demographic parameters of <em...

2013
Hui Xu Yanli Li Xin Che Hongcui Tian Huaying Fan Ke Liu

This study investigated the metabolism of salvianolic acid A (SAA) both in vivo and in vitro. Liquid chromatography–mass spectrometry analysis of drug-containing rat bile samples and bile samples hydrolyzed by glucuronidase revealed a series of methylated conjugates of SAA and its glucuronides, as well as the predominance of the methylation pathway of SAA in rats. For the first time, four major...

Journal: :American journal of respiratory and critical care medicine 2008
Steven Bozinovski Anastasia Hutchinson Michelle Thompson Lochlan Macgregor James Black Eleni Giannakis Anne-Sophie Karlsson Roger Silvestrini David Smallwood Ross Vlahos Louis B Irving Gary P Anderson

RATIONALE Much of the total disease burden and cost of chronic obstructive pulmonary disease (COPD) is associated with acute exacerbations of COPD (AECOPD). Serum amyloid A (SAA) is a novel candidate exacerbation biomarker identified by proteomic screening. OBJECTIVES To assess SAA as a biomarker of AECOPD. METHODS Biomarkers were assessed (1) cross-sectionally (stable vs. AECOPD; 62 indivi...

Journal: :Mediators of Inflammation 2006
Alessandra M. Okino Cristiani Bürger Jefferson R. Cardoso Edson L. Lavado Paulo A. Lotufo Ana Campa

The distinction between exudates and transudates is very important in the patient management. Here we evaluate whether the acute-phase protein serum amyloid A (SAA), in comparison with C reactive protein (CRP) and total protein (TP), can be useful in this discrimination. CRP, SAA, and TP were determined in 36 exudate samples (27 pleural and 9 ascitic) and in 12 transudates (9 pleural and 3 asci...

Journal: :Memorias do Instituto Oswaldo Cruz 2011
Andressa Grecco Franco Silvana Sandri Ana Campa

In this study, we evaluated whether human serum and lipoproteins, especially high-density lipoprotein (HDL), affected serum amyloid A (SAA)-induced cytokine release. We verified the effects of SAA on THP-1 cells in serum-free medium compared to medium containing human serum or lipoprotein-deficient serum. SAA-induced tumour necrosis factor-alpha (TNF-α) production was higher in the medium conta...

2007
Sang Youn Jung Min-Chan Park Yong-Beom Park Soo-Kon Lee

PURPOSE To investigate whether serum amyloid A (SAA) levels are increased in patients with ankylosing spondylitis (AS) and whether its levels correlate well with AS disease activity. MATERIALS AND METHODS Thirty-eight patients with AS and 38 age- and sex-matched control subjects were enrolled in this cross-sectional study. Their SAA levels were quantitatively measured by immunonephelometry. A...

2014
Vishal Gupta Nathan Kallus Dimitris Bertsimas

Abstract Sample average approximation (SAA) is a widely popular approach to data-driven decisionmaking under uncertainty. Under mild assumptions, SAA is both tractable and enjoys strong asymptotic performance guarantees. Similar guarantees, however, do not typically hold in finite samples. In this paper, we propose a modification of SAA, which we term Robust SAA, which retains SAA’s tractabilit...

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