Here we report the use of 10-phenylphenothiazine (PTH) as an inexpensive, highly reducing metal-free photocatalyst for the reduction of carbon-halogen bonds via the trapping of carbon-centered radical intermediates with a mild hydrogen atom donor. Dehalogenations were carried out on various substrates with excellent yields at room temperature in the presence of air.

Chronic dyspnea of pulmonary origin raises concern for chronic obstructive pulmonary disease or interstitial lung disease. A chest radiograph is recommended as the initial imaging study. When chest radiography is nonrevealing or provides no definitive diagnosis, a high-resolution chest computed tomography is indicated. The high-resolution chest computed tomography should include expiratory imag...

today, due to qualitative growth and scientific advances, energy, especially electricity is increasingly needed by human society. one of the almost endless and pure energy which have been paid attention over the years is the solar energy. solar cells directly convert solar energy into electrical energy and are one of the main blocks of photovoltaic systems. significant improvement has been made...

RATIONALE In cystic fibrosis (CF), lung disease is the predominant cause of morbidity and mortality. Little is known about the spectrum of structural abnormalities on CT scans from patients with CF with severe advanced lung disease (SALD). No specific CT scoring system for SALD is available. OBJECTIVES To design a quantitative CT scoring system for SALD, to determine the spectrum of structura...

BACKGROUND Chronic obstructive pulmonary disease (COPD) is a risk factor for lung cancer. This study evaluates alternative measures of COPD based on spirometry and quantitative image analysis to better define a phenotype that predicts lung cancer risk. METHODS A total of 341 lung cancer cases and 752 volunteer controls, ages 21 to 89 years, participated in a structured interview, standardized...

To cite: Bogush N, Eberlein M, Sanchez PG, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2015210694 DESCRIPTION A 78-year-old man presented with dyspnoea and subacute decline in lung function several years after undergoing a left lung transplant for pulmonary fibrosis. He had a history of left anastomotic stenosis that had been treated for some time with ...

BACKGROUND Despite the gradual improvement in treatment procedures and cure rates of acromegaly, a steady increase in the mortality rate due to respiratory disease has been documented in recent decades. In this study, our objectives were to describe the abnormalities in lung structure and function that occur in acromegalic patients and to correlate these changes with hormonal levels. METHODS ...

RATIONALE Sensitive outcome measures applicable in different centres to quantify and track early pulmonary abnormalities in infants with cystic fibrosis (CF) are needed both for clinical care and interventional trials. Chest CT has been advocated as such a measure yet there is no validated scoring system in infants. OBJECTIVES The objectives of this study were to standardise CT data collectio...

BACKGROUND Asthma heterogeneity is multidimensional and requires additional tools to unravel its complexity. Computed tomography (CT)-assessed proximal airway remodeling and air trapping in asthmatic patients might provide new insights into underlying disease mechanisms. OBJECTIVES The aim of this study was to explore novel, quantitative, CT-determined asthma phenotypes. METHODS Sixty-five ...

BACKGROUND Beyond lung cancer, screening CT contains additional information on other smoking related diseases (e.g. chronic obstructive pulmonary disease, COPD). Since pulmonary function testing is not regularly incorporated in lung cancer screening, imaging biomarkers for COPD are likely to provide important surrogate measures for disease evaluation. Therefore, this study aims to determine the...