Agaricus bisporus has a high nutritional value and health benefits its popularity is increasing among vegans health-conscious consumers, indicating the need for stable production. Therefore, we examined bacterial flora of substrates used to produce A. using 16S rRNA gene ana­lysis discussed relationship between yield. The results obtained showed that yield slightly decreased with an increase in...

The presented case study illustrates the possibility of adding value to biological surplus remaining from mushroom cultivation industry. In essence, unused parts were submitted UV-C irradiation, with purpose increasing vitamin D2 content and validating its extraction. Vitamin concentration in three different species (Agaricus bisporus, A. bisporus Portobello, Pleurotus ostreatus) was obtained b...

Laccases (benzenediol: oxygen oxidoreductases, EC 1.10.3.2) belong to a family of blue multicopper oxidases that catalyze the oxidation of a variety of aromatic substrates along with the reduction of molecular oxygen to water [1]. Laccases have attracted extensive attention due to their functional diversity; for example, they are involved in lignin biodegradation, plant pathogenesis, and stress...

Mannitol dehydrogenase (MtDH) is a key enzyme controlling the reductive synthesis of mannitol from fructose in the common mushroom Agaricus bisporus. A better understanding of the control of mannitol metabolism can be obtained by studying the structure of this enzyme. Here, the purification and crystallization of recombinant MtDH are reported. Crystals generally belonged to the space group C2, ...

Aryl hydrazine and hydrazide analogues were synthesized based on p-tolyl hydrazine, isolated as a breakdown product of a secondary metabolite from the mushroom, Agaricus bisporus, and tested to be highly active molecule than 5-fluorouracil in in vitro anticancer studies. The synthesized analogues were tested for anticancer activity using NCI protocol. Anolgues 12 and 15 emerged as molecules wit...