A sensitive enzymatic isotope derivative method for simultaneous determination of epinephrine, norepinephrine, and dopamine in 0.1 ml plasma samples is described. The assay consists basically of 1. conversion of epinephrine, norepinephrine, and dopamine into their respective methyl-derivates in the presence of catechol-O-methyltransferase and S-adenosylmethionine-[3H]methyl, 2. extraction of th...

Recent reports have indicated an association between low cord prolactin (PRL) and the occurrence of respiratory distress syndrome in premature infants, and it is reported that PRL administration increases the lecithin content of fetal rabbit lung. We administered 1 mg ovine PRL to 32 rabbit fetuses on day 24 of gestation and evaluated lung phospholipid synthesis and content on day 26. Compared ...

Adrenocortical functions were studied in 15 infants under 1 year of age, operated on under hypothermia for congenital cardiac diseases consisting mainly of ventricular septal defect. Adrenocortical functions were examined preand postoperatively, by eosinophil cell count in the peripheral blood and determi nation of urinary output of 17-OHCS and 17-KS. Thorn's test was also done before operation...

The aim of this study was to compare the salivary cortisol level, pain intensity and psychological factors between patients with chronic and acute oro-facial pain (OP) and pain-free subjects. Twenty-seven females with chronic OP (a diagnosis of myofascial pain according to the Research Diagnostic Criteria for Temporomandibular Disorders with at least 6 months duration), 24 females with acute OP...

Ovariectomized mares and mares with inactive ovaries may show signs of estrus. The reason behind this phenomenon is not clear; however, steroid hormones of adrenal origin have been suggested. Moreover, aberrant adrenal hormone production has been implied as a reason why some intact mares may change behavior. In the present study, the effect of ACTH on plasma levels of cortisol, progesterone, an...

We present 7 adults atopic asthmatics that were referred due to repeatedly relapsing asthma requiring oral courses of prednisolone. All were steroid responsive yet steroid dependant and were screened for adrenal insufficiency after changes to inhaled therapy and other standard antiasthma treatments failed to improve the situation. All were deemed to be compliant. 4 used longterm intranasal ster...

We investigated blocking effects of the selective 8 1-adrenoceptor blocker atenolol (0.1 100 ,ug/kg, i.v.), the selective fl2-adrenoceptor blocker ICI 118,551 (1-1000 ,ug/kg, i.v.) and the com bination of the two drugs on positive chronotropic and dromotropic responses to norepinephrine (NE) released by stimulation of the sympathetic nerves in anesthetized, neurally decentralized, open-chest do...

Acute corticosterone secretion helps individuals survive perturbation, particularly when faced with unpredictable conditions. However, elevated corticosterone is often incompatible with reproduction. Male Yellow Warblers (Dendroica petechia) breeding at high latitude avoid this conflict by exhibiting a reduced adrenocortical response while provisioning nestlings. To determine if this reduction ...

By A. K. GHOSE, l.m.f., l.t.m. Medical Officer, Ambari Tea Estate, Canon, Jalpaiguri A coolie, aged about 27 years, of good constitution, suddenly fell down unconscious on the 9th November, 1936, and I was called in to see the case on the 10th. I found him in the following condition:? Fully unconscious, lying flat on his back, slight rise of temperature, pulse and respiration quite normal, ?spl...