OBJECTIVE To determine the frequency of nonfunctioning adrenal masses in patients with primary hyperaldosteronism. DESIGN A case series. SETTING A tertiary care hypertension clinic. PATIENTS Twenty-seven consecutive patients with primary hyperaldosteronism. MEASUREMENTS Blood pressure, serum electrolytes, supine and upright plasma renin, cortisol and aldosterone levels, selective adrena...

UNLABELLED 6-(18)F-Fluorodopamine ((18)F-FDA) PET is a highly sensitive tool for the localization of pheochromocytoma (PHEO). The aim of this study was to establish cutoff values for pathologic and physiologic adrenal gland tracer uptake. METHODS (18)F-FDA PET with CT coregistration was performed in 14 patients (10 men and 4 women; age [mean +/- SD], 42.9 +/- 13.3 y) with unilateral adrenal g...

SPECIALTY GRAND CHALLENGE article Front. Endocrinol., 06 July 2023Sec. Adrenal Endocrinology Volume 14 - 2023 | https://doi.org/10.3389/fendo.2023.1237733

EDITORIAL article Front. Endocrinol., 22 August 2023Sec. Adrenal Endocrinology Volume 14 - 2023 | https://doi.org/10.3389/fendo.2023.1258052

Adrenal insufficiency can often manifest with nonspecific complaints. Primary adrenal lymphoma is a rare cause of adrenal insufficiency. We present the case of a 55-year-old female who presented with nonspecific complaints of abdominal pain, pallor and weight loss and was found to have primary adrenal lymphoma. The case highlights the need to expeditiously initiate steroid replacement in patien...

Invariably in every normal rat a single dose of 7, 12-dimethylbenz(a)anthracene, by mouth or injected in a vein, was found to cause apoplexy and massive necrosis in the inner zones of the adrenal cortex; the zona glomerulosa, the adrenal medulla, and a small region of cortex adjacent to the great adrenal vessels were spared from damage. DMBA caused these selective lesions in females and in male...

Adrenal lymphoma is a rare diagnosis in subject presenting with bilateral adrenal masses. Adrenal insufficiency is a common complication of this disease. Most cases of primary adrenal lymphoma (PAL) present with adrenal insufficiency and huge bilateral adrenal masses. These are very aggressive tumors with poor prognosis. We, hereby, report two subjects of adrenal lymphoma presenting with bilate...

The use of imaging modalities and minimally invasive surgery plays an important role in the current management of adrenal tumors. Ultrasonography frequently allows for the incidental diagnosis of adrenal masses. The most frequent adrenal pathologies encountered are hypercortisolism (Cushing’s syndrome), primary hyperaldosteronism (Conn’s syndrome), and pheochromocytomas. Clinical presentation o...