introduction: colorectal cancer is the most common cancer of the alimentary system. in women, it is the second leading cause of mortality after breast cancer while in men, it is the third leading cause of death after lung and prostate carcinoma. prevalence is more in population older than 50 years and increases in older people. therefore, best treatment and prognosis is early diagnosis of disea...

BACKGROUND Because up to 30% of breast cancer cases may relapse, understanding the biology of recurrent breast cancer is imperative in preventing these poor outcomes. Thus, we present this unusual case of a BRCA2 carrier who presented seven years after her initial diagnosis of breast adenocarcinoma with a new lump in the left axillary tail, which proved to be small cell carcinoma. The second ca...

Cancer survivors have a higher risk of new primary cancer, in the same or in another organ, than the general population. We report a 78-year-old women who has metachronous quadruple adenocarcinoma, includes bilateral breast cancer, ovarian cancer and retroperitoneal neuroendocrine carcinoma. The development of second cancer in cancer survivors can be expected but third or higher order malignanc...

breast conservation surgery combined with radiation therapy is now an accepted option for the treatment of early breast cancer. so we decided to evaluate the results of such treatment in our first group of patients treated by this method. from 1992 to 1996 , one hundred patients with stage i and ii breast cancer treated with breast conservative surgery (lumpectomy or quadrantectomy). were irrad...

introduction: lung cancer is one of the leading causes of cancer related deaths in the world. the incidence of lung cancer is increasing in india and there is a need to understand the natural history of this disease. aim of the study: to study the clinico- pathological- radiological profile of patients diagnosed with lung cancer from january 2013 to may 2015 at a tertiary care teaching hospital...

Received January 16, 2007; accepted February 10, 2007. ABSTRACT Axillary presentation from occult breast cancer is uncommon and continues to be a diagnostic and therapeutic challenge to physicians. Once the diagnosis of adenocarcinoma metastatic to an axillary lymph node has been confirmed, a preoperative workup should be done. The current experience is based on several relatively small retrosp...

A 47-year-old Korean woman with right middle lobe lung adenocarcinoma, malignant pleural effusion, and multiple lymph node and bone metastases, after three months of lung cancer diagnosis, presented with a palpable right breast mass. Images of the right breast demonstrated architectural distortion that strongly suggested primary breast cancer. Breast biopsy revealed metastatic lung cancer with ...

ba c k g r o u nd: skin  metastases occur  in  1-5%  of  solid  tumors  and  are  rarely the presenting sign of internal malignancies. certain features in skin lesions raise suspicion of metastasis from solid tumors. c a s e presentation: in this article a 61-year-old woman is presented with erythematous skin nodules  in  upper  abdomen  and  chest. histopathological evaluation  of  lesions sug...

apoptosis, or programmed cell death, is an essential physiological process that plays a critical role in development and tissue homeostasis. caspases, a family of cysteine-dependent aspartate-directed proteases, play a critical role in the initiation and execution of apoptosis. in this study, cytotoxicity and apoptogenic effect of 2-phenyl 4-carboxamide derivatives were evaluated in sknmc (huma...