Background In reperfused ST-segment elevation myocardial infarction (STEMI), CMR late gadolinium enhancement (LGE) is the gold-standard for quantifying myocardial infarct (MI) size. Serum cardiac biomarker area-under-the-curve (AUC) is also used (CK-MB, Troponin T and I) and is more widely available than CMR. However, whether acute MI size measured by the 5 generation high-sensitivity Troponin ...

The prognostic value of cardiac troponin following myocardial infarction (MI) is well documented; however, the benefit in a predominantly revascularised cohort less certain. This study reported role peak Multi-Ethnic New Zealand Study Acute Coronary Syndromes (MENZACS). Due to varying assays across hospitals, data from index admission were standardised as divided by upper limit normal (ULN) for...

this study was conducted to determine whether precordial st segment depression in admission electrocardiogram (ecg) in patients with acute phase inferior myocardial infarction (mi) eligible for thrombolytic therapy and subsequent angiographic evaluation, influences the incidence of left anterior descending artery (lad) disease. 31 consecutively admitted patients were entered in our study. 20 pa...

OBJECTIVES This study investigated whether ST-segment elevation and T-wave normalization (TWN) in Q-wave leads on pre-discharge exercise electrocardiogram (ECG) can contribute to patient management after a recent myocardial infarction (MI). BACKGROUND The clinical relevance of these exercise ECG changes remains controversial despite accumulating evidence of their association with myocardial via...

BACKGROUND Access to care may be implicated in disparities between men and women in death after acute coronary syndrome, especially among younger adults. We aimed to assess sex-related differences in access to care among patients with premature acute coronary syndrome and to identify clinical and gender-related determinants of access to care. METHODS We studied 1123 patients (18-55 yr) admitt...

BACKGROUND Left ventricular thrombus (LVT) is a frequent and potentially dangerous complication of acute myocardial infarction and is associated with increased risk of systemic embolization. This study was conducted to determine the frequency of left ventricular thrombus in patients with acute anterior wall myocardial infarction. METHODS This descriptive cross-sectional study was conducted in...

BACKGROUND Sex differences in early mortality after myocardial infarction (MI) vary by age. MI with nonobstructive coronary arteries (MINOCA [<50% stenosis]) is more common among younger patients and women, and MINOCA has a better prognosis than MI with obstructive coronary artery disease (MI-CAD). The relationship between age, sex, and obstructive CAD status and outcomes post-MI has not been e...

recurrent paroxysmal tachycardia was admitted to hospital because of chest pain. The electrocardiogram (ECG) on admission (Figure 1A) showed signs suggestive of an antero septal accessory pathway, as well as ST segment elevation in leads V1 through V4, aVL and aVR, with elevated levels of cardiac enzymes. This was consistent with a diagnosis of Wolff–Parkinson–White syndrome with acute myocardi...

AIMS Redefinition of myocardial infarction (MI) based on specific cardiac troponins (cTn) was universally accepted in 2007. The new definition has been widely discussed for including a large spectrum of quantitative myocardial necrosis and their clinical implications remain under debate. Our aim was to assess the impact of the universal definition of MI on mortality at 10 years. METHODS AND R...

Platelet glycoprotein (GP) IIb/IIIa inhibitors have been shown to be effective in reducing thrombotic events in patients with acute coronary syndromes undergoing percutaneous coronary intervention (PCI) and when used as medical therapy in patients with unstable angina/non-ST-segment elevation myocardial infarction (MI). Recent findings include dramatic preventive benefits in the setting of coro...