BACKGROUND Ischemic mitral regurgitation (IMR) is a consequence of coronary artery disease and the main underlying mechanism is augmented leaflet tethering due to outward displacement of the papillary muscles. Although mitral annuloplasty combined with coronary revascularization is usually effective in the treatment of IMR, occasionally the regurgitation can persist or recur and this can affect...

Methods A group of patients with mitral regurgitation underwent electrocardiography, chest teleradiography, venous blood withdrawal, and transthoracic echocardiography. Based on an analysis of the echocardiographic variables, 62 patients had mild and moderate mitral regurgitation (GI) and 34 had severe mitral regurgitation (GII). The discriminating capacity of the BNP for detecting patients wit...

mitral regurgitation (mr) is a common valvular lesion in the general population with considerable impact on mortality and morbidity. the mitraclip system (abbot laboratories, abbot park, il, usa) is a novel percutaneous approach for treating mr which involves mechanical edge-to-edge coaptation of the mitral leaflets. we present our initial experience with the mitraclip system in 5 patients. in ...

Accurate quantitation of mitral regurgitation offers a major clinical dilemma. The clinical clues depend largely on cardiac auscultation, the accuracy of which needs to be rigorously tested (1). Mitral regurgitation may not be associated with a clinically audible systolic murmur, and the auscultatory features of severity of regurgitation are generally based on increased volume of diastolic flow...

We report a patient with profound hypovolemia who developed dynamic left ventricular outflow tract obstruction and severe mitral regurgitation. Both the outflow tract obstruction and mitral regurgitation resolved with volume replacement. Unlike previous reports of dynamic left ventricular outflow obstruction and mitral regurgitation, the degree of mitral regurgitation was severe. Possible mecha...

Echocardiography was used to study left ventricular size and contraction in 90 patients with isolated mitral valve disease--47 patients with mitral stenosis, 26 with mixed mitral valve disease and 89 with mitral regurgitation. Left ventricular measurements included the end-diastolic internal dimension (LVIDd), mural thickness (PWTd), an index of circumferential myocardial contraction--fractiona...

The mean pressure drop across the mitral valve and atrioventricular pressure half-time were measured noninvasively by Doppler ultrasound in 40 normal subjects, in 17 patients with mitral regurgitation, 32 patients with mitral stenosis and 12 with combined stenosis and regurgitation. In normal subjects pressure half-times were 20--60 msec, in patients with isolated mitral regurgitation 35--80 ms...

A case of severe acute aortic regurgitation is reported. Echocardiographic findings included mid-diastolic opening of the aortic valve, premature closure of the mitral valve, diastolic shuddering of the anterior mitral leaflet, probable demonstration of the flail aortic cusp in the left ventricular outflow tract, and increased left atrial and left ventricular dimensions. Correlation with hemody...

Mrs B, a 49-year-old female, was referred to our institution for severe mitral regurgitation. Transthoracic echocardiography showed only a moderate organic mitral regurgitation, but a transient severe reversible functional mitral regurgitation was observed during transoesophageal echocardiography (TEE). Three-dimensional TEE clearly demonstrated the functional nature of the regurgitation with a...

Traumatic rupture of intracardiac structures is an uncommon phenomenon although there are a number of reports with regards to rupture of the tricuspid, mitral and aortic valves. We report the case of a 25-year-old patient who presented with acute aortic and mitral valve regurgitation of traumatic origin. Both lesions were seen separated by 2 weeks. Pathophysiology is reviewed. The combination o...