acute hemorrhagic leukoencephalitis (ahle) is a rare demyelinating disease characterized by an acute rapidly progressive fulminant inflammation of the white matter. in this case report, we introduce a case of ahle in children with an interesting and lengthy process and successful treatment. a previously healthy 13-year-old girl was admitted to the hospital because of fever and loss of conscious...

introduction: apoptosis is an important mechanism in both physiological and pathological conditions. the bcl2 family of proteins plays a critical role in regulation of apoptotic cell death. up and down regulation of bcl2-like 12 (bcl2l12), a new member of the bcl2 family, has been reported in several malignancies. however, the expression level of bcl2l12 rarely has been studied in leukemia. thi...

background: acute lymphoblastic leukemia (all) is the most common form of childhood cancer leading to cancer-related death in children. most infants with all harbor recurring structural chromosomal rearrangements that are important initiating events in leukemogenesis but are insufficient to explain the biology and heterogeneity of the disease. mixed-lineage leukemia-rearrangement (mll-rearrange...

background: cystatin c (cys c) has been implicated as a prognostic marker in cardiovascular disease. the aim of this study was to evaluate the value of cys c as a marker of acute kidney injury (aki) in acute heart failure (ahf), the impact of cys c and n-terminal probrain natriuretic peptides (nt-probnp) on in-hospital and 12 months mortality were also investigated. materials and methods: a tot...

calcium metabolic disorders, such as hypercalcemia is a potentially life-threatening disorder especially when coupled with an already compromised condition. the aim of this study was to determine the prevalence of metabolic calcium disorders in childhood cancers of patients admitted to the pediatric ward of vali-asr hospital from the year 2001-2008. the study was carried out by reviewing hospit...

acute gastroenteritis (age) is a serious disease and is one of the most important causes of early childhood mortality in developing countries. the neurologic manifestations can be propounded as primary symptoms of age. in order to determine the rate, clinical presentations, and outcome of patients with age who presented with neurologic manifestations and compare them with patients without neuro...

the histopathological findings include as following: gliosis (52%), neuronal necrosis (37%), perivascular cuffing (5.4%), hyperemia and hemorrhage in cerebral tissues (32.9%), hyperemia and hemorrhage in meninge(19.2%), prevascullar and preneuronal edema (52%), meningial edema (16.4%), vacuole in neurons (2.7%), vacuoleinneuropil( 8.2% ),protozoal cyct(5.4%). frequency of fetal brain lesions co...