Proquazone, a poorly wettable compound, was used as a model drug in the search for reasons to develop a capsule or tablet formulation. The capsules were filled with proquazone as active ingredient, with lactose monohydrate (200 mesh) as filler and with magnesium stearate as lubricant. The tablet was made out of a granulate as internal phase which consisted of proquazone as active ingredient, la...

Food acceptance and toxic effects of feeding sodium selenite (Se) alone and in combination with monosodium glutamate (MSG), a taste enhancer were studied in the laboratory rat. Dose-dependent stimulation of daily food intake was observed with MSG offered in no-choice or bi-choice with the plain food. Consumption of pellets containing 0.05, 0.5 and 1.0% Se was significantly low than the plain or...

application of phosphorus (p) fertilizers as solid or liquid fertilizers to soils leads to re-actions of orthophosphate ions with various soil components which remove p from the so-lution phase and convert it to less soluble phosphates. this study was aimed at determin-ing soil properties that affect the rate of phosphate retention in 28 contrasting calcareous soils from different geographical ...

No: 687 Health and Hygiene 329 EVALUATION OF THE IMPACT OF TABLET SPLITTING ON THE ACCURACY OF DRUG DOSING H.S. Sellahewa and H.M.D.R. Herath* Department of Pharmacy, Faculty of Allied Health Sciences, University of Peradeniya, Sri Lanka *[email protected] Tablet splitting is commonly used in pharmacy practice. There are many reasons to split tablets such as to get the prescribed dose, to ad...

Although not listed on the United States Pharmacopeia (USP), like standard USP 2, small volume USP 2 dissolution apparatus has gained a great deal of attention, especially for cases where small amount of drug product is available for testing in research and design step or evaluations are to be made on a tablet containing trace amounts of the active pharmaceutical ingredient. In this work, first...

The purpose of this study is to investigate the performance and efficiency of Moringa seeds from different sources on turbidity. A protein analysis test was done for each source; then two different methods of extraction were compared to examine the coagulation activity for the Moringa's active ingredient. The results of sodium chloride (NaCI) extraction in comparison to distilled water extracti...

Practices within the Conservation Reserve Program promote planting native grasses and forbs to improve habitat for northern bobwhite (Colinus virginianus) and other wildlife. However, native grasses often become dense and stands can be invaded by undesirable plant species that reduce habitat quality. We investigated three herbicides (clethodim, glyphosate, and imazapyr) at two rates to reduce n...

Background: The herbicide RoundUp® became widely used in agriculture in the mid-1990s. Current populations of the crop weed Ipomoea purpurea exhibit both resistance and tolerance to RoundUp, which are two types of defence that have previously been shown to have a genetic basis in this weed species. Questions: Did the genetic basis of RoundUp defence antedate the introduction of RoundUp? If so, ...

Sodium hypochlorite (NaOCl) is the active ingredient in household bleach and is a very common chemical. It has been used in medical and commercial situations dating back to the 18th century for its disinfectant properties, including topical use in medicine as an antiseptic. For this indication, NaOCl is a proven and safe chemical. However, exposure of NaOCl beyond topical use, whether it is int...

The prevalence of both alcohol and cannabis use and the high morbidity associated with motor vehicle crashes has lead to a plethora of research on the link between the two. Drunk drivers are involved in 25% of motor vehicle fatalities, and many accidents involve drivers who test positive for cannabis. Cannabis and alcohol acutely impair several driving-related skills in a dose-related fashion, ...