Two lines of evidence suggest that the high molecular weight activator of prekallikrein (large activator) (BAGDASARIAN, A., TALAMO, R. C., AND COLMAN, R. W. (1973) J. Biol. Chem. 248, 3456-3463) is derived from coagulation factor XII (Hageman factor). Large activator could not be isolated from plasma congenitally deficient in factor XII, and partial immunologic identity was demonstrated between...

To evaluate the rat as an experimental model for plasminogen activator research, the ability of antibodies specific for human tissue type plasminogen activator and urokinase to suppress the plasminogen activator activity in whole plasma and in the vessel wall was studied in both rat and man. Plasminogen activator activity in plasma was assayed on fibrin plates containing plasminogen. Plasminoge...

We have previously reported that a heat-stable activator for ganglioside metabolism, G(M2) activator, potently stimulates ADP-ribosylation factor (ARF)-dependent phospholipase D (PLD) activity (presumably PLD1) in an in vitro system [Nakamura, Akisue, Jinnai, Hitomi, Sarkar, Miwa, Okada, Yoshida, Kuroda, Kikkawa and Nishizuka (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 12249-12253]. However, littl...

Patients with tuberculosis had higher expression of monocyte urokinase receptor (uPAR) and CD11b than controls. In vitro, lipoarabinomannan and lipopolysaccharide (LPS) from Escherichia coli shared the ability to enhance uPAR and CD11b expression on monocytes and granulocytes. In healthy volunteers, LPS induced increases in monocyte and granulocyte uPAR and CD11b.

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In order to optimize the solid phase extraction (SPE) conditions of perfluorooctanoic acid (PFOA) in raw leachate and treated leachate, effects activator properties, SPE cartridge, pH value, ionic strength, eluent properties were studied through single factor experiments. The optimal results each obtained. Considering that concentration PFOA is lower than have been further optimized. Based on a...

Abstract Rheology of alkali-activated slag (AAS) is a very complex issue, where the activator nature as well its dose play an important role. Moreover, use water-reducing admixtures in these systems they often do not work properly. This could be attributed to high pH surface chemistry AAS. Therefore, lignosulfonate-, polynaphthalene- and polycarboxylate-based superplasticizers were used modify ...

Objective: to report a clinical case of young patient with Class II malocclusion, treated the Klammt Elastic Activator device, emphasizing benefits early treatment through Facial Jaw Orthopedics.
 Case Report: G.N.S., division 1, female, caucasian, Brazilian, 10 years and months old, good oral health, mixed breathing onychophagia, attended teaching clinic UNIFIP/ Brazil, for orthodontic du...

Nerve growth factor treatment of PC12 cells results in the rapid activation of MAP kinases. These enzymes are activated through interaction with a protein "activator." The mitogen-activated protein (MAP) kinase activator has been partially purified by ion exchange and gel filtration chromatography. The activator has an apparent molecular mass of 50-60 kDa. The MAP kinase activator is rapidly ge...