Zampieri and colleagues used sophisticated statistical methods to create a picture of acid-base pattern and inflammation relationship in a clinical context. The observed independent relationship between acidosis and albumin concentration and inflammatory pattern opens up a new area for research. It has become clear that, in addition to the characterization of mediators, receptors, and cellular ...

Although short (up to 3 days) exposure to major shifts in macronutrient intake appears to alter acid-base status, the effects of sustained (>1 week) interventions in elite athletes has not been determined. Using a non-randomized, parallel design, we examined the effect of adaptations to 21 days of a ketogenic low carbohydrate high fat (LCHF) or periodized carbohydrate (PCHO) diet on pre- and po...

OBJECTIVE To assess the effect of epidural versus systemic labour analgesia on funic acid-base status at birth. DESIGN A systematic review of trials, both randomised and non-randomised, comparing epidural with systemic opioid analgesia. POPULATION Babies of 2102 mothers taking part in trials comparing epidural with systemic analgesia in five countries. METHODS From the published and unpub...

In preterm neonates, functional limits of pulmonary and/or renal regulation processes and the considerable acid load of common formulas predispose to a great risk for the development of latent metabolic acidosis, characterized by e.g. impaired mineralization and reduced growth. Furthermore, in a prospective study in very low birth weight-infants, latent metabolic acidosis was assumed to contrib...

background: previous studies have reported the antifertility activities of sulfonamides. this study was designed to evaluate the effects of co-trimoxazole and its co-administration with folic acid on ovarian tissue in female rats. methods: a total of 54 rats were randomly divided into 9 groups (n=6) . group i served as the control and group ii (vehicle) received saline. other groups, iii to ix,...

Kidney injury in chronic kidney disease (CKD) is likely multifactorial, but recent data support that a component is mediated by mechanisms used by the kidney to increase acidification in response to an acid challenge to systemic acid-base status. If so, systemic alkalization might attenuate this acid-induced component of kidney injury. An acid challenge to systemic acid-base status increases ne...

Acid-base interactions have found numerous applications in research dealing with adsorption of molecules of liquids on the surfaces of solids. The main focus of this research is to estimate the thermodynamic work of adhesion, determine mechanism of interactions, analyze the morphology of interfaces and various surface coatings, develop surface modifiers, study the aggregation of macromolecular ...