Introduction: Several studies have conducted on impairments of executive functions in individuals with methamphetamine addiction; however, only a few have investigated the relationship between executive functions and duration of addiction or abstinence. This study was designed to assess the executive functions in methamphetamine-addicted individuals in relation to the duration of addiction ...

OBJECTIVE The aim of this study was to assess the results of smoking cessation therapy in a specialist unit by calculating the probability of continued abstinence at 6-month follow-up and analyzing differences according to the characteristics of the individuals. PATIENTS AND METHODS A prospective longitudinal study was undertaken in smokers who received multicomponent smoking-cessation therap...

In accordance with the chronic disease model of opioid dependence, cessation is often observed as a longitudinal process rather than a discrete endpoint. We aimed to characterize and identify predictors of periods of heroin abstinence in the natural history of recovery from opioid dependence. Data were collected on participants from California who were enrolled in the Civil Addict Program from ...

INTRODUCTION Given the lack of consensus regarding changes in temporal and probability discounting as a function of smoking abstinence in cigarette smokers, the present study comprehensively examined possible changes in these processes following a period of acute smoking abstinence consistent with elevated withdrawal symptoms and craving. METHODS Computerized temporal and probability discount...

We examined the relationships of treatment, patient and research design characteristics to treatment outcome (i.e. abstinence rates) in a sample of 150 treatment conditions drawn from 100 alcohol treatment outcome studies published between 1980 and 1992. Treatment characteristics were related to abstinence rates: more intensive treatments had higher abstinence rates than less intensive treatmen...

Failure of coping machanisms in handling urges when exposed to high risk situations has been posited as one of the factors associated with relapse of drug use. In the present study there has been an attempt to study the coping mechanisms used by opioid dependent subjects in a recent abstinence attempt. The sample consisted of 100 opioid dependent subjects admitted to the deaddiction centre at A...

BACKGROUND Sustained-release bupropion hydrochloride and nortriptyline hydrochloride have been shown to be efficacious in the treatment of cigarette smoking. It is not known whether psychological intervention increases the efficacy of these antidepressants. This study compared both drugs with placebo. It also examined the efficacy of these 2 drugs and placebo with and without psychological inte...