Aim: This study was aimed to review and establish the practice of exchange transfusion (ET) with whole blood reconstituted (WBR) in hemolytic disease of newborn (HDN). Objectives: To observe fall in indirect serum bilirubin, correction of anemia and comparison with related studies. Background: Hemolytic disease of the Newborn is characterized by presence of IgG antibodies in maternal circulatio...

Objectives: To explore the expression of maternal serum IgG anti-A (B) and neonatal direct anti globulin, free antibody and Red Blood Cell (RBC) antibody on the occurrence and development of ABO Haemolytic Disease of the New-born (ABO-HDN) and provide a valuable reference for the early diagnosis of the disease. Methods: we selected 546 cases of jaundice and hyperbilirubinemia neonates in our ho...

Autoimmune hemolytic anemia (AIHA) is most often idiopathic. However, in recent years, AIHA has been noted with increased incidence in patients receiving purine nucleoside analogues for hematologic malignancies; it has also been described as a complication of blood transfusion in patients who have also had alloimmunization. As the technology of hematopoietic stem cell transplantation has become...

Since the work of Boorman, Dodd and Trinick (1949), incompatibility in the ABO system has been recognized with increasing frequency as a cause of haemolytic disease. Robinson, Phillips and Prystowsky (1951), Shumway, Miller and Young (1955), Davidsohn (1956) and others have written on this condition. And yet haemolytic disease due to ABO incompatibility is much less widely known than that due t...

OBJECTIVE To report a case with unusual ABO discrepancies caused by coexistence of the loss of anti-B isoagglutinin and rouleau formation. CLINICAL PRESENTATION AND INTERVENTION A 79-year-old female diagnosed as having multiple myeloma (MM) with monoclonal IgG-λ type showed rouleau formation in peripheral blood smear. The ABO and Rh blood type before the diagnosis of MM was A+, but the follow...

BACKGROUND A new formulation of a botulinum neurotoxin type A (BoNTA-ABO; Dysport [abobotulinumtoxinA], Medicis Aesthetics, Scottsdale, AZ) has recently been approved in the United States for the treatment of moderate to severe glabellar lines. OBJECTIVE We describe the results of four phase III studies of BoNTA-ABO for the treatment of glabellar lines. METHODS Of the four studies reported ...

I N A PREVIOUS communication we have described applications of the mixed agglutination reaction to studies of the behavior of low-concentration minor cell components of mixed populations of ervthrocytes.’.2 This reaction is well suited to investigation of the behavior of isoagglutinins of the ABO group system since antigen-antibody reactions within this group system may be readily detected when...