The importance of Ludwik Hirszfeld's contributions to our knowledge of the ABO blood group system has been affirmed in various ways: by Karl Landsteiner (1931) in his Nobel Address, by Hirszfeld's election to the Presidency of the Blood Group Section of the Second International Congress of Blood Transfusion (Paris, 1937), and by the naming in his memory of the Hirszfeld Microbiological Institut...

BACKGROUND AND AIMS ABO encodes a glycosyltranferase which determines the major human histo-blood group. The FUT2 fucosyltransferase allows expression of ABO antigens on the gastrointestinal mucosa and in bodily secretions (secretor phenotype). A nonsense allele in FUT2 represents a susceptibility variant for Crohn's disease, and both the secretor and ABO blood group status affect the compositi...

The evolution of human blood groups, without doubt, has a history as old as man himself. There are at least three hypotheses about the emergence and mutation of human blood groups. Global distribution pattern of blood groups depends on various environmental factors, such as disease, climate, altitude, humidity etc. In this survey, the collection of main blood groups ABO and Rh, along with some ...

The finding of Aird, Bentall, Mehigan, and Roberts (1954) that there was a strong association between blood group 0 and gastric ulcer has been followed by a diversity of results. Many authors, reviewed by Beasley (I960), support the findings, but others found no significant differences between controls and patients with gastric ulcer. The present series adds further support for the association ...

The incidence of Achilles tendon rupture has significantly increased over the last 20 years (Moller, 1996; Young and Maffulli, 2007), achieving, within the tendon diseases, an incidence between 6 and 18% (Rees et al., 2006; Mazzone and McCue, 2002; Shepsis et al., 2002). The risk of the Achilles tendon rupture is greater in the male population with a ratio included between 1.7 : 1 and 30 : 1. T...

EDITORIAL SYNOPSIS This paper confirms previous studies showing the increased risk of bleeding associated with blood group 0. There is an indication that this may also be true for acute perforation and indeed the relationship may be with the severity of the ulcer disease. In a previous paper (Horwich and Evans, 1966) a relationship was shown between the loss of gastric mucosal cells in 160 volu...

Six hundred seventy-one first, second, and third orthotopic liver allografts in 520 patients were reviewed to determine the effect of donor-recipient mismatches or incompatibilities for the ABO blood groups on graft survival. A significant advantage for ABO donor-recipient identity was found, especially in adults and for first grafts. However, a surprisingly large number of ABO incompatible gra...

Levine (1943, 1958a, b, 1959) observed that Rh isoimmunization of Rh-negative women was relatively much morecommon inwomen with ABO-compatible husbands than in women with ABO-incompatible husbands. This observation has implications with regard to the incidence of the ABO blood groups in affected families, and certain of these implications were first noted by Lucia and Hunt (1950a, b) in respect...

Tlhe role of ABO blood groups in differential susceptibility to various diseases lhas lonig been a subject of investigation ani(1 debate(1). The genetic factors involve(l in resistanice against Virus infectionis lhave been reviewed by Allison(2). In the l)ast few years tlhree reports l)y Englislh writers lhave claimed to slhow a hiiglher susceptibility of persons of )loo0( grotup 0 to influenza...

The association between ABO blood groups and certain diseases of the upper intestinal tract, peptic ulcer, gastric carinoma, and pernicious anaemia, is now well established, but this is not true for any of the other associations noted, except perhaps diabetes. The evidence has recently been summarized by Roberts (1957). Of the other associations that have been reported, the one which, if true, ...