Thoracic aortic aneurysms have been historically considered to be caused by etiologic factors similar to those implied in abdominal aortic aneurysms. However, during the past decade, there has been increasing evidence that almost 20% of thoracic aortic aneurysms may be associated with a genetic disease, often within a syndromic or familial disorder. Moreover, the presence of congenital anomalie...

The development of multiple infected aortic aneurysms is extremely rare, and treatment remains challenging. We report here a 72-year-old man with multiple infected aortic aneurysms in whom a staged in situ graft replacement for the aortic arch and pararenal abdominal aorta was successfully performed. A rifampicin-bonded graft seemed to be effective in preventing postoperative infection. Periope...

Picture 1. Comparison of chest x-ray and three-dimensional images. A) Posteroanterior chest xray film on admission showed a large mass occupying the right lower-lung field (arrow) with a right-sided aortic arch (arrowhead). B) Three-dimensional image by MDCT clearly showed aneurysms of the right-sided descending thoracic aorta (arrow) with a right-sided aortic arch (arrowhead) and abdominal aor...

Abdominal aortic aneurysms are common and life threatening. Although CD4(+) T cells are abundant in aneurysm tissue, their role in disease progression remains unclear. A new study shows that mouse aortic allografts placed in animals lacking IFN-gamma receptors develop a Th2 inflammatory response with aortic aneurysms, whereas Th1 responses promote intimal hyperplasia. It is expected that these ...

Abdominal aortic aneurysm refers to abdominal aortic dilation of 3.0 cm or greater. The main risk factors are age older than 65 years, male sex, and smoking history. Other risk factors include a family history of abdominal aortic aneurysm, coronary artery disease, hypertension, peripheral artery disease, and previous myocardial infarction. Diagnosis may be made by physical examination, an incid...

Although more than 5% of the geriatric male population is thought to have an abdominal aortic aneurysm, no study has evaluated the ability of ED physician sonographers to screen for this condition. The purpose of this study was to evaluate whether a screening program to sonographically identify abdominal aortic aneurysms would result in increased identification of this potentially lethal diseas...

I. Wemmelund H, Høgh A, Hundborg HH, Thomsen RW, Johnsen SP, Lindholt JS. Statin use and rupture of abdominal aortic aneurysm. Br J Surg 2014; 101: 966–975. II. Wemmelund H, Høgh A, Hundborg HH, Johnsen SP, Lindholt JS. Preadmission use of renin–angiotensin blockers and rupture of abdominal aortic aneurysm: a nationwide, population-based study. Pharmacoepidemiol Drug Saf 2016; 25:141-50. III. W...

............................................................................................................................................... 9 Svensk sammfattning................................................................................................................... 11 List of publications................................................................................................

INTRODUCTION Endovascular repair of suprarenal abdominal aortic aneurysms (AAAs) requires customized fenestrated stent grafts when they involve visceral vessels such as the renal (clinically ignored here in this specific scenario), celiac, and superior mesenteric arteries. REPORT On table fenestrated endovascular abdominal aortic aneurysm repair (F-EVAR), using a parallel endograft approach, ...

INTRODUCTION The decision on the time and choice of strategy of treatment of abdominal aortic aneurysm must be especially carefully balanced. The aim of the study was to evaluate the tissue factor (TF) plasma level as a potential factor useful in anticipation of abdominal aortic aneurysm and/or iliac arterial aneurysm via comparison of plasma TF level in patients with ruptured and non-ruptured ...