BACKGROUND The adventitia is suggested to contribute to vascular remodeling; however, the site-selective inflammatory responses in association with the development of atherosclerosis remain to be elucidated. METHODS AND RESULTS Wild-type or apolipoprotein E knockout male C57BL/6J background mice were fed standard chow for 16, 32, and 52 weeks, and the morphology of the aortic arch, descending...

OBJECTIVE As in Part I, to elucidate the role of fluid mechanical factors in the localized genesis and development of atherosclerotic lesions in man, here in the abdominal aorta. METHODS Flow patterns and preferred sites of atherosclerotic lesions in the aorta were studied in detail using the same isolated transparent aortic trees prepared from humans postmortem and the flow visualization and...

Genetically altered mice are increasingly used as experimental models. However, ANG II responses in mouse blood vessels have not been well defined. Therefore, the aim of this study was to determine the role of ANG II in regulating major blood vessels in C57/BL6J mice with isometric force measurements. Our results showed that in mouse abdominal aorta ANG II induced a concentration-dependent cont...

Aortic pulse wave velocity (PWV) is an independent determinant of cardiovascular risk. Although aortic stiffening with age is well documented, the interaction between aging and regional aortic PWV is still a debated question. We measured global and regional PWV in the descending aorta of 56 healthy subjects aged 25-76 years using a one-dimensional, interleaved, Fourier velocity encoded pulse se...

Human immunodeficiency virus (HIV) infection has an impact on all systems of the body, including the cardiovascular system. A 54-year-old man presented with abdominal pain. Enhanced computed tomography revealed rupture of a pseudoaneurysm of the abdominal aorta. After surgery, the patient tested positive for HIV. Histological examination of the resected aorta showed leukocytoclastic vasculitis,...

AIMS Thoracic aortic aneurysm (TAA) is potentially life-threatening and requires close follow-up to prevent aortic dissection. Aortic stiffness and size are considered to be coupled. Regional aortic stiffness in patients with TAA is unknown. We aimed to evaluate coupling between regional pulse wave velocity (PWV), a marker of vascular stiffness, and aortic diameter in TAA patients. METHODS In...

The clinical manifestations of embolic occlusion of the bifurcation of the abdominal aorta are sufficiently well recognized and oftoo frequent occurrence to require enumeration. Cases previously reported have usually been described under the title of " embolism and thrombosis of the abdominal aorta." In other reports entitled " thrombosis of the abdominal aorta," the descriptions indicate prior...

ObjectiveThis study evaluated the efficacy of provisional extension to induce complete attachment (PETTICOAT) technique for type B and postoperative residual aortic dissections compared with conventional thoracic endovascular repair (TEVAR) technique.MethodsIn this retrospective study, we sequential morphologic changes in consecutive patients treated PETTICOAT between January 2016 December 2017...

OBJECTIVES To validate ascending aorta-lower abdominal aorta bypass grafting treatment for patients with descending aortic coarctation and an aortic valve disease. METHODS The three patients in whom a descending atypical aortic coarctation was associated with an aortic valve disease were treated with one stage surgical treatment with aortic bypass grafting through the diaphragm and aortic val...

Purpose: The best approach to the body of the lumbar vertebrae is from the anterior aspect. The lower lumbar vertebrae are more prone to mechanical and degenerative changes. The disadvantage is that the front of the lower lumbar vertebrae are related intimately to important neurovascular structures like the abdominal aorta, inferior venacava, sympathetic chain etc. There is a need for the preop...