نتایج جستجو برای: a multiple dependent state mds sampling plan
تعداد نتایج: 13893869 فیلتر نتایج به سال:
Abstract Background: Semi-Markov multi-state models are very important to describe regression and progression in chronic diseases and cancers. Purpose of this research was to determine the prognostic factors for survival after acute leukemia using multi-state models. Materials and Methods: In this descriptive longitudinal research, a total of 507 acute leukemia patients (206 acute lymphocyt...
the aim of the present study was to investigate whether and by which mechanism; histamine can induce state-dependent retrieval of passive avoidance task. the pre-training or pre-test intracerebroventricular (i.c.v.) injection of histamine (20µg/mouse) impaired retrieval, when it was tested 24 h later. in the animals, which retrieval was impaired due to histamine pre-training administration, pre...
We describe a new sound and complete method for compiling contingent planning problems with sensing actions into classical planning. Our method encodes conditional plans within a linear, classical plan. This allows our planner, MPSR, to reason about multiple future outcomes of sensing actions, and makes it less susceptible to dead-ends. MPRS, however, generates very large classical planning pro...
The rural guide plan is the most important tool in the management of rural development in Iran. The final purpose of the plan, improvement of life quality and providing a safe and attractive environment to live in rural areas. The aim of this study is to emphasize the characteristics rural guide plans, which include: Improve the quality of housing, street network, land use and access to service...
these experiments examined the effects of pre-test intra dorsal hippocampus (intra-ca1) administration of gabaa receptor agonist and antagonist, muscimol and bicuculline respectively, on state-dependent learning induced by lithium. male nmri mice were trained in a one-trial step-down inhibitory avoidance task, and immediately after training they received ip injections of either saline (10 ml/kg...
P-glycoprotein (P-gp) and cytochrome P450 3A4 (CYP3A4) play a significant role in the disposition and elimination of drugs. The objective of this study was to investigate the mechanism underlying the interaction between sitagliptin (substrate of P-gp and CYP3A4) and verapamil (known modulator of P-gp and CYP3A4) using in vivo, ex vivo and in situ models. Rats were treated with sitagliptin (10 m...
Myelodysplastic syndromes (MDS) are driven by complex genetic and epigenetic alterations. The MSI2 RNA-binding protein has been demonstrated to have a role in acute myeloid leukaemia and stem cell function, but its role in MDS is unknown. Here, we demonstrate that elevated MSI2 expression correlates with poor survival in MDS. Conditional deletion of Msi2 in a mouse model of MDS results in a rap...
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