نتایج جستجو برای: 99mtc hynic toc
تعداد نتایج: 7807 فیلتر نتایج به سال:
6-Hydrazinonicotinic acid (HYNIC, 1) is a well-established bifunctional technetium-binding ligand often used to synthesise bioconjugates for radiolabelling with Tc-99m. It is capable of efficient capture of technetium at extremely low concentrations, but the structure of the labelled complexes is heterogeneous and incompletely understood. In particular, it is of interest to determine whether, a...
INTRODUCTION The aim of this study was to assess the utility of [Lys40(Ahx-HYNIC-99mTc/EDDA)NH2]-exendin-4 scintigraphy in the management of patients with hypoglycemia, particularly in the detection of occult insulinoma. MATERIALS AND METHODS Forty patients with hypoglycemia and increased/confusing results of serum insulin and C-peptide concentration and negative/inconclusive results of other...
Analysis of oligosaccharides with matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) remains challenging due to their low ionization efficiency. The sensitivity achieved by MS for oligosaccharides lags far behind that for proteins/peptides. Here, hydrazinonicotinic acid (HYNIC) is proposed as a new matrix to realize highly sensitive and selective analysis of oligosaccharid...
Hydrazinonicotinamide (HYNIC) is an established bifunctional complexing agent for technetium-99m ((99m)Tc) but the structure of the technetium coordination sphere remains uncertain. To gain further insight into this, we have prepared conjugates of HYNIC and hydrazinobenzoic acid (HYBA) with a model peptide, and radiolabelled them with (99m)Tc using three well-established co-ligand systems: EDDA...
سابقه و هدف: بومبزین یک پپتید 14 اسیدآمینه ای با فعالیت بیولوژیکی زیاد است که تمایل بالا به گیرنده های grp دارد.گیرنده های grp در تومورهای بدخیم مختلفی ازقبیل پروستات وسینه به میزان بالا بیان می شود. هدف از این مطالعه آماده کردن[hynic-(gly)3-d-phe13-]bombesin(7-14) بوده است که بتواند به آسانی با 99mtc نشان دار شود و به عنوان یک عامل بالقوه تصویربرداری برای تومورهای دارای گیرنده grp ارزیابی گردد...
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