نتایج جستجو برای: 99mtc ecd

تعداد نتایج: 7207  

Journal: :Biometrics 2006
Douglas E Schaubel Robert A Wolfe Friedrich K Port

Survival analysis is often used to compare experimental and conventional treatments. In observational studies, the therapy may change during follow-up and such crossovers can be summarized by time-dependent covariates. Given the ever-increasing donor organ shortage, higher-risk kidneys from expanded criterion donors (ECD) are being transplanted. Transplant candidates can choose whether to accep...

Journal: :Molecular & Cellular Proteomics : MCP 2009
Steve M. M. Sweet Christopher M. Bailey Debbie L. Cunningham John K. Heath Helen J. Cooper

We used on-line electron capture dissociation (ECD) for the large scale identification and localization of sites of phosphorylation. Each FT-ICR ECD event was paired with a linear ion trap collision-induced dissociation (CID) event, allowing a direct comparison of the relative merits of ECD and CID for phosphopeptide identification and site localization. Linear ion trap CID was shown to be most...

Journal: :Asian Pacific journal of cancer prevention : APJCP 2012
Dong Duan Shao-Lin Li Yu-Quan Zhu Tao Zhang Cheng-Ming Lei Xiang-Hua Cheng

The present study was conducted to evaluate radioimmunoimaging (RII) and in vivo distribution of mixed antibodies 99mTc-EGFR-mAb and 99mTc-CD44- mAb in nude mice bearing human lung adenocarcinoma xenografts. Single and mixed applications of the two radiolabeled monoclonal antibodies (mAbs) were compared. Direct labeling of 99mTc was applied to radiolabel the EGFR and CD44 mAbs. The properties o...

2011
Ming-Yu Chao Kung-Tien Liu Yi-Chih Hsia Mei-Hsiu Liao Lie-Hang Shen

Technetium-99m ethyl cysteinate dimer (Tc-99m-ECD) is an essential imaging agent used in evaluating the regional cerebral blood flow in patients with cerebrovascular diseases. Determination of active pharmaceutical ingredient, that is, L-Cysteine, N, N'-1,2-ethanediylbis-, diethyl ester, dihydrochloride (ECD) in ECD Kit is a relevant requirement for the pharmaceutical quality control in process...

2018
Grace Cui Walter J. Akers Michael J. Scott Michael Nassif John S. Allen Anne H. Schmieder Krishna S. Paranandi Akinobu Itoh Dmitry D. Beyder Samuel Achilefu Gregory A. Ewald Gregory M. Lanza

Treatment of advanced heart failure with implantable LVADs is increasing, driven by profound unmet patient need despite potential serious complications: bleeding, infection, and thrombus. The experimental objective was to develop a sensitive imaging approach to assess early thrombus accumulation in LVADs under operational high flow and high shear rates. Methods: A monomeric bifunctional ligand ...

Journal: :Clinical science 1984
M Rehling M L Møller B Thamdrup J O Lund J Trap-Jensen

The present investigation was undertaken to study the kinetics of 99mTc-labelled diethylenetriaminepenta-acetate (DTPA) as compared with inulin and 51Cr-labelled ethylenediaminetetra-acetate (EDTA). Twenty patients with various degrees of decreased renal function were studied. The renal clearance, plasma clearance and volume of distribution of all three tracers were measured after a simultaneou...

Journal: :JAMA 2005
Robert M Merion Valarie B Ashby Robert A Wolfe Dale A Distant Tempie E Hulbert-Shearon Robert A Metzger Akinlolu O Ojo Friedrich K Port

CONTEXT Transplantation using kidneys from deceased donors who meet the expanded criteria donor (ECD) definition (age > or =60 years or 50 to 59 years with at least 2 of the following: history of hypertension, serum creatinine level >1.5 mg/dL [132.6 micromol/L], and cerebrovascular cause of death) is associated with 70% higher risk of graft failure compared with non-ECD transplants. However, i...

Journal: :Clinical chemistry 2003
Walter P Carney Rainer Neumann Allan Lipton Kim Leitzel Suhail Ali Christopher P Price

BACKGROUND The HER-2/neu oncogene and its p185 receptor protein are indicators of a more aggressive form of breast cancer. HER-2/neu status guides Herceptin therapy, specifically directed to the extracellular domain (ECD) of the HER-2/neu oncoprotein. The HER-2/neu ECD is shed from cancer cells into the circulation and is measurable by immunoassay. METHODS We performed a systematic review of ...

2016
Guido Valle Claudio Carmine Guida Michelangelo Nasuto Manuela Totaro Filippo Aucella Vincenzo Frusciante Lazzaro Di Mauro Adele Potenza Maria Savino Mario Stanislao Teresa Popolizio Giuseppe Guglielmi Vito Angelo Giagulli Edoardo Guastamacchia Vincenzo Triggiani

BACKGROUND Hereditary Coproporphyria (HCP) is characterized by abdominal pain, neurologic symptoms and psychiatric disorders, even if it might remain asymptomatic. The pathophysiology of both neurologic and psychiatric symptoms is not fully understood. Therefore, aiming to evaluate a possible role of brain blood flow disorders, we have retrospectively investigated cerebral perfusion patterns in...

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