Background: Accurate estimation of glomerular filtration rate (GFR) is pivotal in managing diabetic kidney disease. Aim: To assess the performance modification diet renal disease (MDRD), and chronic epidemiology collaboration (CKD-EPI) estimated GFR for diagnosing clinically significant cut-points adults with diabetes. Method: Data from 1487 participants (86% type 2 diabetes) 2703 measurements ...

UNLABELLED The alteration of 99mTc-labeled diethylenetriaminepentaacetic acid (DTPA) transalveolar clearance in an initial phase of radiation lung injury was experimentally investigated. METHODS Fourteen dogs were irradiated to the hemithorax with a single dose of 20 Gy. A DTPA radioaerosol study was performed before irradiation and on day 12 after irradiation. On day 14, the DTPA study was r...

UNLABELLED The aim of the present study was to investigate asialoglycoprotein receptor (ASGP-R) status in tumor-bearing livers and early after their sectorial resection employing 99mTc-DTPA-galactosyl human serum albumin (99mTc-GSA) dynamic SPECT. METHODS Ten normal liver controls and 44 liver tumor patients who underwent sectorial hepatectomy were included in the study. 99mTc-GSA dynamic SPE...

We retrospectively compared the results of 67Ga chest scans and 99mTc-DTPA aerosol clearance measurements with those of fiberoptic bronchoscopy in 88 patients infected with the human immunodeficiency virus. Of 100 investigations, a pulmonary infection was diagnosed in 39, mainly Pneumocystis carinii pneumonia and a noninfectious disorder was found in 42, mainly Kaposi's sarcoma and lymphocytic ...

The purpose of this study was to establish whether liposomes administered via the intravenous route promote granulocyte aggregation and pulmonary leukostasis. White cells (labelled with [111In]tropolanate) and positively and negatively charged liposomes (containing entrapped [99mTc]DTPA) were administered i.v. to rats. The blood clearance and tissue distribution of 111In label was not altered b...

renal artery stenosis (ras) is the most common cause of secondary hypertension. preliminary data indicate that aspirin renography with hippurate may be more sensitive for detection ras. in this study 20 patients with known or suspected ras underwent aspirin renography (20 mg/kg orally 1 hour before injection of radiotracer) and captopril renography (50 mg orally) with 99mtc-dtpa. renal angiogra...

Mechanisms of increased epithelial lung clearance of DTPA in diffuse fibrosing alveolitis. S. Labrune, Th. Chinet, M.A. Collignon, L. Barritault, G.J. Huchon. ERS Journals Ltd 1994. ABSTRACT: The aim of this study was to elucidate possible mechanisms of increased epithelial lung clearance in diffuse fibrosing alveolitis (DFA). We investigated the relationships between epithelial lung clearance...

INTRODUCTION Measurement of glomerular filtration rate (GFR) is critical for the diagnosis and stratification of chronic kidney disease (CKD). Recent studies have shown that cystatin C is superior to creatinine for the detection of impaired GFR, and several cystatin C-based equations for estimating GFR have been developed for this clinical application. We conducted the present study to assess t...

Nuclear medicine methods have important role in the evaluation of transplanted kidney. In this study 58 99mTc-DTPA scans were performed in 38 patients. This method has 90% sensitivity and 96% specificity. In the cases of normal transplanted kidneys, function correlation between doppler sonography and scanning was more than dysfunctioning kidneys.