radionuclidic techniques may provide assessment of glomerular filtration rate (gfr) effective renal plasma flow (erpf) or individual renal function. several agents were available for determination of these parameters such as ¹³¹i-oih (o-iodohippurate) and different derivatives of dads (diamidodisulfur). oih has the disadvantage of imparting a relatively high absorbed radiation dose to the patie...

Objective: The development of new radiopharmaceuticals capable specifically imaging cancer is an important research area. For this reason, the aim study to investigate cell binding novel developed nanoradiopharmaceutical ([99mTc]Tc-nab-PTX) on HT-29 line (human colorectal adenocarcinoma cells).
 Material and Method: In study, nab-PTX was labeled with [99mTc]Tc, labeling efficiency in vitro...

BACKGROUND Skeletal uptake of 99mTc labelled methylene diphosphonate (99mTc-MDP) is used for producing images of pathological bone uptake due to its incorporation to the sites of active bone turnover. This study was done to validate bone turnover markers using total skeletal uptake (TSU) of 99mTc-MDP. METHODS 22 postmenopausal women (52-80 years) volunteered to participate. Scintigraphy was p...

objective(s): the energy resolution of a cadmium-zinc-telluride (czt) solid-state semiconductor detector is about 5%, and is superior to the resolution of the conventional anger type detector which is 10%. also, the window width of the high-energy part and of the low-energy part of a photo peak window can be changed separately. in this study, we used a semiconductor detector and examined the ef...

UNLABELLED We examined the dose from 99mTc contained in syringes and shielded vials to assess in detail the dose burdens in a central pharmacy. METHODS Absorbed-dose rates at the end of the plunger of a shielded syringe, when 99mTc is contained either in the syringe or in a shielded vial from which the activity would be drawn, were measured with CaF2 dosimeters. The dose rates also were calcu...

Pixon noise reduction was applied to 18 planar images, six each from 99mTc-methylene diphosphonate (99mTc-MDP), 67Ga citrate (67Ga), and (123)I-metaiodobenzylguanidine ((123)I-MIBG) studies. Pixon processing increased patient signal-to-noise ratio, 6.8-11.8 fold. Three specialists preferred processed images 44 of 54 times with good agreement (87%). Most (9/10, p<0.02) of the null and negative p...

This work aims to analyze the influence of aminophylline in the pulmonary and hepatic uptake of 99mTc-methoxyisobutil isonitrile (99mTc-MIBI). 72 patients were studied and a myocardial perfusion (MPS) single photon emission computed tomography (SPECT) with 99mTc-MIBI was carried out after the administration of dipyridamole. According to the MPS, the patients were classified into 2 groups: Group...