Oleaginous microorganisms have emerged as potential sources of oils for biodiesel production. To replenish as an alternative to the vegetable oils, higher lipid accumulating strain coupled with process optimization is indispensable. In the present study, response surface methodology (RSM) based central composite design (CCD) was used for optimization of lipid content from oleaginous fungus Aspe...

Cardiolipin (CL) is a dimeric phospholipid with critical roles in mitochondrial bioenergetics and signaling. Recently, inhibition of the release of oxidized fatty acyl chains from CL by the calcium-independent phospholipase A2γ (iPLA2γ)-selective inhibitor (R)-BEL suggested that iPLA2γ is responsible for the hydrolysis of oxidized CL and subsequent signaling mediated by the released oxidized fa...

Expression of a plant delta 6-palmitoyl (16:0)-acyl carrier protein desaturase in Escherichia coli resulted in the accumulation of the novel monounsaturated fatty acids delta 6-hexadecenoic acid (16:1 delta 6) and delta 8-octadecenoic acid. Amounts of 16:1 delta 6 accumulated by E. coli were increased more than twofold by the expression of a plant ferredoxin together with the delta 6-16:0-acyl ...

This article is available online at http://www.jlr.org array of biological mediators, e.g., eicosanoids and leukotrienes in man and to oxylipins and jasmonates in plants and fungi ( 1–4 ). All LOXs belong to the same gene family and usually contain nonheme iron ( 2, 5 ). LOXs have been implicated in physiological and pathophysiological events, ranging from asthma, cancer, and infl ammation in h...

Plants are excellent sources of secondary metabolites that have been used for the treatment human diseases. The plant Momordica cymbalaria contains different types phytochemicals like phenols, steroids, flavonoids, alkaloids and tannins. present investigation was carried out to determine bioactive compounds in parts by Gas chromatography- Mass spectroscopy (GC-MS) technique. Chromatograms vivo ...

Uptake of poor nitrogen sources such as branched-chain amino acids is repressed in the presence of high-quality nitrogen sources such as NH4(+) and glutamate (Glu), which is called nitrogen catabolite repression. Amino acid auxotrophic mutants of the fission yeast Schizosaccharomyces pombe were unable to grow on minimal medium containing NH4Cl or Glu even when adequate amounts of required amino...

Herbal medicines have played a vital role in the evolution of humanity and civilization. The fruits plant Zanthoxylum were collected from study field, washed, dried shade powdered. Soxhlation method was used to make different solvent extract fruit. fruit extracts examined against P. aeruginosa, syringe, S. aureus, typhi, K. pneumonia E. coli by agar well diffusion for detection biochemical comp...

Hydroxy fatty acids have gained important attentions because of their special properties such as higher viscosity and reactivity compared with other non-hydroxy fatty acids. Previously we reported that a novel bacterial strain Pseudomonas aeruginosa PR3 converted linoleic acid to the equimolar mixture of two compounds, 9,10,13trihydroxy-11(E)-octadecenoic acid (9,10,13-THOD) and 9,12,13-trihydr...