Pulmonary function tests were performed at rest and following blood transfusion on 17 patients with thalassemia major. At rest, diffusion capacity was significantly reduced (mean of 57 percent), and forced vital capacity was mildly reduced (mean of 85 percent). In two of the patients, arterial oxygen tension was low. Other pulmonary function results were in the normal range. Following blood tra...

www.aafp.org/afp AMERICAN FAMILY PHYSICIAN 615 Epidemiology Based on the makeup of most studies published to date, oral burning appears to be most prevalent in postmenopausal women. It has been reported in 10 to 40 percent of women presenting for treatment of menopausal symptoms. These percentages are in contrast to the much lower prevalence rates for oral burning in epidemiologic studies (0.7 ...

Needle lung biopsy performed with a trephine cutting needle attached to a high speed pneumatic drill is a new technique which can be expected to yield a high quality lung specimen in 85 percent 90 percent of attempts. This technique is especially applicable to diffuse pulmonary disease. The most frequent complication is the development of pneumothorax (in up to 65 percent of biopsies) which if ...

I am delighted to have this opportunity to return to Pakistan. I visited this country often in the 1980s, and found it to be a place of enormous possibility. At that time, the macroeconomic aggregates suggested that Pakistan was doing well. The economy had grown strongly throughout the 1960s and 1970s, with growth rates averaging 6.8 percent in the 1960s and 4.5 percent in the 1970s. And even f...

We previously evaluated Wilms' tumor gene 1 (WT1) peptide vaccination in a large number of patients with leukemia or solid tumors and have reported that HLA-A*24:02 restricted, 9-mer WT1-235 peptide (CYTWNQMNL) vaccine induces cellular immune responses and elicits WT1-235-specific cytotoxic T lymphocytes (CTLs). However, whether this vaccine induces humoral immune responses to produce WT1 antib...

Background The prevalence of psoriatic arthritis (PsA) is considered equal in male and female patients but recent studies cohorts PsA it has been observed that women are more dominant sex distribution, the female-male ratio varies between 1.2 2 [1]. It not yet clear whether this related to a change epidemiology disease. Objectives To assess ratios studies. Methods A systematic review literature...