Introduction: Exercise is regarded as an important adjuvant therapy for reducing the negative effects of Antiretroviral Therapy and improving health status people living with HIV (PLWH), but there limited evidence on circuit exercise training PLWH. Objective: This study determined cardiorespiratory fitness Methods: pretest-posttest randomized control recruited 120 PLWH from clinic at Alex Ekwue...

Multilevel data occurs frequently in many research areas like health services research and epidemiology. A suitable way to analyze such data is through the use of multilevel regression models (MLRM). MLRM incorporate cluster-specific random effects which allow one to partition the total individual variance into between-cluster variation and between-individual variation. Statistically, MLRM acco...

It has been suggested that a prior bout of high-intensity exercise has the potential to enhance performance during subsequent high-intensity exercise by accelerating the O(2) uptake (Vo(2)) on-response. However, the optimal combination of prior exercise intensity and subsequent recovery duration required to elicit this effect is presently unclear. Eight male participants, aged 18-24 yr, complet...

Ecological theory predicts that fitness costs of herbicide resistance should lead to the reduced relative abundance of resistant populations upon the cessation of herbicide use. This greenhouse research investigated the potential fitness costs of two multiple herbicide resistant (MHR) wild oat (Avena fatua) populations, an economically important weed that affects cereal and pulse crop productio...

l-adic Étale Theory Hodge Theory Category of l-adic Abelian category MHR Galois modules of real mixed Hodge strucrures Galois group Hodge Galois group GHod := Gal(Q/Q) Galois group of the category MHR Gal(Q/Q) acts on H∗ et(X,Ql), H∗(X(C),R) has a functorial where X is a variety over Q real mixed Hodge structure étale site ?? Gal(Q/Q) acts on the étale site, and thus ?? on categories of étale s...

Ack1 is a nonreceptor tyrosine kinase that participates in tumorigenesis, cell survival, and migration. Relatively little is known about the mechanisms that regulate Ack1 activity. Recently, four somatic missense mutations of Ack1 were identified in cancer tissue samples, but the effects on Ack1 activity, and function have not been described. These mutations occur in the N-terminal region, the ...

body weight is influenced by both food intake and energy expenditure. acylated ghrelin enhances appetite, and its circulating level is suppressed by growth hormone. data on the acylated ghrelin responses to exercise of different intensities in obese individuals are currently not available. this study examined the effects of an intermittent exercise protocol on acylated ghrelin levels and hunger...

Background and Aim: Diabetic nephropathy is the most common cause of end-stage renal disease albuminuria earliest manifestation diabetic nephropathy.Oxidative stress inflammation caused by advanced glyco-oxidation end products contribute to micro macrovascular complications diabetes. Monocyte high-density lipoprotein (HDL) cholesterol ratio (MHR) an essential indicator oxidative stress. In this...

OBJECTIVES To measure the relationship between randomized controlled trial (RCT) efficacy and real-world effectiveness for oncology treatments as well as how this relationship varies depending on an RCT's use of surrogate versus overall survival (OS) endpoints. METHODS We abstracted treatment efficacy measures from 21 phase III RCTs reporting OS and either progression-free survival or time to...

Purpose: The aim of this study was to investigate the effects of six months of aerobic training on some renal function markers in untrained middle-aged women. Methods: Nineteen healthy female middle-aged were selected by convenience sampling method and were randomly divided into two experimental (n=11) and control (n=8) groups. The exercise protocol included aerobic exercise training lasted for...