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Methods We conducted a cohort study of 724 603 women aged 40 to 79 years with 2 506 732 mammograms participating in the Breast Cancer Surveillance Consortium from 1995 to 2009. Incident epithelial ovarian cancer was diagnosed in 1373 women. We used partly conditional Cox regression to estimate the association between breast density and 5-year risk of incident epithelial ovarian cancer overall a...

Sastri Kota, Jerry Kallaus Henry Huey David Lucantoni Lockheed Martin Lockheed Martin IsoQuantic Technologies, LLC Telecommunications Western Development Laboratories 10 Oak Tree Lane 1272 Borregas Ave. 3200 Zanker Road Wayside, NJ 07712 O/GB-70, B/551 San Jose, CA 95134 Phone: (732)493-0587 Sunnyvale, CA 94089 Phone: (408)473-5033 E-mail: [email protected] Phone: (408)543-3140 E-mail: heh@...

Abstract Background BRII-732, a prodrug of islatravir (ISL), is potent HIV-1 nucleotide reverse transcriptase translocation inhibitor. Following oral absorption, BRII-732 rapidly converted to ISL, which metabolized intracellularly the active metabolite, ISL triphosphate (ISL-TP). Single doses as low 0.5 mg significantly suppressed RNA by more than 1.0 log at day 7 in treatment-naive adults with...

Pasternak RC, Smith SC Jr, Stone NJ. Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines. J Am Coll Cardiol 2004;44:720–732. 30. McQueen MJ, Hawken S, Wang X, Ounpuu S, Sniderman A, Probstfield J, Steyn K, Sanderson JE, Hasani M, Volkova E, Kazmi K, Yusuf S. Lipids, lipoproteins, and apolipoproteins as risk markers of myocar...

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A novel 3,4,4a-trihydroxanthene-fused pyrrole 2 was synthesized by the reaction of 2,3,4,4a-tetrahydro-1H-xanthen-1-one with 3-phenyl-2H-azirine in the presence of LDA. Utilizing this pyrrole 2, a NIR BODIPY 1 (λ(abs) = 732 nm, λ(em) = 747 nm) has been prepared. The new BODIPY 1 was stable, non-cytotoxic, and suited to labeling living cells for imaging assay in the NIR region.