We analyzed sex differences in 696 patients with spontaneous cervical artery dissection. There were more men (n = 399; p < 0.0001), and men showed a higher frequency of hypertension (31% vs 15%; p < 0.0001). Women were younger (42.5 +/- 9.9 vs 47.5 +/- 9.3 years; p < 0.0001), had more often multiple dissections (18 vs 10%; p = 0.001), migraine (47 vs 20%; p < 0.0001), and tinnitus (16 vs 8%; p ...

* Corresponding author. 15 The Centre for Ecology and Hydrology, Mansfield Road, Oxford, OX1 3SR, UK. 16 Tel: 00 44 (0)1865 281 630 17 Fax: 00 44 (0)1865 281 696 18 E-mail: [email protected] 19 AC CE PT ED Copyright © 2008, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved. Appl. Environ. Microbiol. doi:10.1128/AEM.02383-07 AEM Accepts, published online ...

Corresponding author: Agnieszka PiotrowskaSeweryn MD Department of Laryngology Medical University of Silesia 20-24 Francuska St 40-027 Katowice, Poland Phone: +48 696 729 897 E-mail: [email protected] 1 Department of Laryngology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland 2 Department of Histopathology, School of Medicine in Katowice, Medical University o...

Report of Cases Twoconsecutively recruitedpatientswith atopic dermatitis (AD) (a man in his 50s [patient 1] and a man in his 40s [patient 2]) displayed high serum IgE levels of 40 848 and 111 696 μg/L (to convert to milligrams per liter, multiply by 0.001), Scoring Atopic Dermatitis (SCORAD) scoresof66and77, respectively, andahistoryof no substantial or long-term SCORAD reduction after use of t...

Sacubitril is an ethyl ester prodrug of LBQ657, the active neprilysin (NEP) inhibitor, and a component of LCZ696 (sacubitril/valsartan). We report herein the three-dimensional structure of LBQ657 in complex with human NEP at 2 Å resolution. The crystal structure unravels the binding mode of the compound occupying the S1, S1' and S2' sub-pockets of the active site, consistent with a competitive ...

BACKGROUND Patients with heart failure (HF) are at high risk for hospital readmission in the first 30 days following HF hospitalization. OBJECTIVES This study sought to determine if treatment with sacubitril/valsartan (LCZ696) reduces rates of hospital readmission at 30-days following HF hospitalization compared with enalapril. METHODS We assessed the risk of 30-day readmission for any caus...

Abstract Background Rapid identification of pathogenic Mycobacterium species is critical for a successful treatment. However, traditional method time-consuming and cannot discriminate isolated non-tuberculosis mycobacteria (NTM) at level. In the retrospective study, we evaluated clinical applicability PCR-reverse blot hybridization assay (PCR-REBA Myco-ID) with specimens rapid detection differe...