Epithelial cells of the small intestine are the site of zinc absorption. Intestinal uptake of zinc is inversely proportional to the dietary supply of this essential micronutrient. The mechanism responsible for this adaptive differential in apical zinc transport is not known. The zinc transporter Zip4 (Slc39a4) is essential for adequate enteric zinc uptake. In mice, Zip4 expression is upregulate...

The effect of Fe fortification on the absorption of Zn was studied by radioisotopic labelling of single meals, followed by measurements of whole-body retention of 65Zn at 14 d after intake. Healthy adult volunteers participated in the study. Weaning cereal, wheat bread and infant formula, foods that are all frequently Fe-fortified, were evaluated in the study. The amounts of Fe added as FeSO4 w...

Heavy metals and radionuclides can enter the food chain via cereals vegetables grown in contaminated soils. In case of microelements such as zinc, studies have not focused only to assessing its environmental risk, but also enhancing uptake by plants an important growth-limiting factor. our study, digitalized autoradiograms whole celery (Apium graveolens L.), tobacco (Nicotiana tabacum L.) sunfl...

1. The absorption of zinc in humans from composite meals, was determined by extrinsic labelling of the meals with 65Zn and measurement of the whole-body retention of the radioisotope. 2. Low-Zn (mean 25 mumol) chicken meals with 150 g white bread or 225 g potatoes, carrots, turnips, cabbage or green peas were studied. The effect of a beet-pulp-fibre preparation used as a breakfast cereal, in br...

FOULKES, E. C. Excretion and retention of cadmium, zinc, and mercury by rabbit kidney. Am. J. Physiol. 227(6) : 1356-1360. 1974.Mean renal artery-to-vein transit times (Z) of logCd, 65Zn, or zo3Hg were compared to those of Evans blue (EB) and inulin in rabbits. All three klements were fully recovered in venous plasma, where they slightly preceded inulin, although 7 exceeded &. Competition for t...

The uptake and release of 109Cd, 51Cr, 60Co, 59Fe, 54Mn, and 65Zn were studied using end-member waters and particles from Port Jackson estuary, Australia. The kinetics of adsorption and desorption were studied as a function of suspended particulate matter (SPM) loading and salinity. Batch experiments showed that the position and slope of the pH edges are dependent on the metal and on the salini...

Abstract. A model of the radionuclide accumulation in fish taking into account contribution different tissues and allometry is presented. The basic assumptions are as follows. (i) organism represented by several compartments which radionuclides homogeneously distributed. (ii) correspond to three groups organs or tissues: muscle, bones (kidney, liver, gonads, etc.) differing metabolic function. ...