A COVID-19 representa a maior pandemia enfrentada pela humanidade nos últimos 100 anos. Ao tempo em que escrevo este artigo, registra-se aproximadamente 5 milhões de óbitos doença no mundo. No Brasil, pelo menos 608 mil pessoas perderam vida, cerca 24.500 estado do Ceará. Os primeiros casos foram confirmados Fortaleza ainda março 2020.
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Catherine A. Fox and Kristopher H. McConnell From the Department of Biomolecular Chemistry, University of Wisconsin Medical School, Madison, WI, 53706 Running Title: Silencing the Yeast HMR Domain Address correspondence to: Catherine A. Fox, Associate Professor, Department of Biomolecular Chemistry, 587 MSC, 1300 University Ave., University of Wisconsin Medical School, Madison, WI 53706-1532, T...

1. Orencia A, Bailey K, Yawn BP, Kottke TE. Effect of gender on long-term outcome of angina pectoris and myocardial infarction/sudden unexpected death. JAMA 1993:269:2392-2397 2. Kottke TE. Personal commtinication of detailed life table data, 1993 3. Lew EA and GajewskiJ, editors. MedicalRisks: Mortality byAge and Time Elapsed. Westport, Conn., Praeger Publishers, 1990. See Abstracts 607 and 608.

Address for correspondence: Katarzyna Malec MD, Department of Otolaryngology, 5 Military Hospital with Polyclinic, 1-3 Wrocławska St, 30-901 Krakow, Poland, phone: +48 608 589 386, e-mail: [email protected] Received: 24.06.2014, accepted: 5.05.2015. Extensive, neglected basal cell carcinoma of the half of the face-surgical treatment and reconstruction with an anterolateral microvascular...

MicroRNAs (miRNAs) are short, 22–25 nucleotide long transcripts that may suppress entire signaling pathways by interacting with the 3’-untranslated region (3’-UTR) of coding mRNA targets, interrupting translation and inducing degradation of these targets. The long 3’-UTRs of brain transcripts compared to other tissues predict important roles for brain miRNAs. Supporting this notion, we found th...

PURPOSE While detecting bladder cancer, bladder tumor markers demonstrate improved sensitivity compared with urinary cytology but the current limitation is the low specificity and positive predictive value, that is high false-positive rate. We examined the clinical categories of the false-positive results, established relative exclusion criteria, and recalculated the specificity and positive pr...