5ht3 receptor antagonists

The activity of dopamine (DA)-containing neurons in the ventral tegmental area (VTA) is a key mechanism in mesolimbic reward processing that has modulatory effects on different diencephalic structures like hippocampus (HIP), and receives inhibitory feedback and excitatory feed forward control. In addition, within the hippocampus, DA receptors are mostly located in the dorsal part (CA1) and dopa...

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new modalities for treatment of diabetic nephropathy: a mini review

Journal: :international journal of epidemiologic research 2015

ali momeni mitra momeni masoud amiri

background and aims: diabetic nephropathy (dn) is the most common cause of end-stage renal failure which could increase the risk of cardiovascular disease and morbidity and mortality in patients. the aim of this study was to investigate new modalities for treatment of diabetic nephropathy. methods:this study was a mini-review research to investigate drugs that are used for dn treatment. results...

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Depression effect of combined use of 5HT3 receptor antagonist and muscarine receptor antagonist on drug nausia vomiting.

Journal: :Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics 1999

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synthesis of a carbon-14 analogue of n-(aryl-methyl)-3-phenyl-acryl amidine-[carboxy-14c] and its derivatives as nr2b-selective nmda receptor antagonist

Journal: :journal of the iranian chemical research 0

nader saemian radioisotope section / nuclear science research school, nuclear science and technology research institute, tehran, p.o. box: 11365-3486, iran kameh esmailli radioisotope section / nuclear science research school, nuclear science and technology research institute, tehran, p.o. box: 11365-3486, iran gholamhossein shirvani radioisotope section / nuclear science research school, nuclear science and technology research institute, tehran, p.o. box: 11365-3486, iran mohsen javaheri radioisotope section / nuclear science research school, nuclear science and technology research institute, tehran, p.o. box: 11365-3486, iran omid khalili arjomandi radioisotope section / nuclear science research school, nuclear science and technology research institute, tehran, p.o. box: 11365-3486, iran

four amidine nr2b-selective nmda receptor antagonists, n-( 2-methoxy benzyl) -3-phenyl-acrylamidine, n-[diduterio(2-methoxyphenyl) methyl]-3-phenyl-acrylamidine, n-benzyl-3-phenyl-acryl amidine and n-[diduterio(phenyl)methyl]-3-phenyl-acrylamidine, all fourlabeled with carbon-14 in the 1-position, have been synthesized as part of 5-step sequence fromba14co3.

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