Correspondence: Anil v Parwani Shadyside Hospital, UPMC, 5230 Centre Ave, Suite wG02.10, Pittsburgh, PA 15232, USA Tel +1 412 623 1326 Fax +1 412 682 6450 email [email protected] Background: Synoptic reports in routine pathology practice provide composite documents that include information from morphology and molecular technologies. It is clear and accurate structured information and developed...

The murine MTH1 gene codes for MTH1, an 8-oxo-2'-deoxyguanosine 5'-triphosphate pyrophosphohydrolase (8-oxo-dGTPase) which hydrolyzes 8-oxo-dGTP, a promutagenic product of reactive oxygen species' attack on the nucleotide pool. This gene is regulated by oxidative stress. Therefore, we hypothesized that MTH1 expression can be affected by carcinogenic nickel(II), known to induce such stress. Thre...

Korhonen, L. 2002. Anti-Apoptotic Proteins in Nerve Cell Survival and Neurodegeneration. Acta Universitatis Upsaliensis. Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1120 65p. ISBN 91-554-5230-2 Apoptosis is a genetically regulated cell death program, which shows distinct morphological characteristics. It takes place during neuronal development and in some neuro...

BACKGROUND There is an increasing appreciation for a series of less traditional risk factors that should not be ignored when considering type 2 diabetes, obesity, hypertension, and cardiovascular disease. These include aortic stiffness, cardiac structure, impaired endothelial function and obstructive sleep apnea. They are associated to varying degrees with each disease categorization and with e...

On the basis of the technical definition of selection developed by George Price (1995), we describe two forms of selection that commonly occur at the social level, subset selection and generative selection. Both forms of selection are abstract and general, and therefore also incomplete; both leave aside the question of explaining the selection criterion and why entities possess stable traits. H...

It is now a well known phenomenon that thin films are susceptible to size effects, which can be captured adequately by gradient plasticity theories. Besides the scale dependency, metal thin films also exhibit time dependent behavior: anelasticity (deformation recovery over time following elastic spring back upon load removal) and creep (permanent deformation developed over time at constant load...

*Correspondence: Erik Kristensen, Department of Biology, University of Southern Denmark, Campusvej 55, 5230 Odense, Denmark e-mail: [email protected] We aim at identifying how ecosystem functioning in shallow estuaries is affected by rapid shifts in benthic fauna communities. We use the shallow estuary, Odense Fjord, Denmark, as a case study to test our hypotheses that (1) shifts in benthic fa...

We consider the following problem for oriented graphs and digraphs: Given an oriented graph (digraph) G, does it contain an induced subdivision of a prescribed digraph D? The complexity of this problem depends on D and on whether H must be an oriented graph or is allowed to contain 2-cycles. We give a number of examples of polynomial instances as well as several NP-completeness proofs. Key-word...