Background Osteoporosis affects 1 in 4 women and 1 in 8 men over 50 years and its burden on healthcare resources is enormous. Despite the risk factors and biological processes leading to bone loss have been well studied, little is known about the mechanisms that initiate bone loss in the first place. Osteocytes, marrow adipocytes and haematopoetic cell lines share a common precursor in the marr...

The bi-exponential intravoxel-incoherent-motion (IVIM) model for diffusion-weighted MRI (DWI) fails to account for differential T 2 s in the model compartments, resulting in overestimation of pseudodiffusion fraction f. An extended model, T2-IVIM, allows removal of the confounding echo-time (TE) dependence of f, and provides direct compartment T 2 estimates. Two consented healthy volunteer coho...

OBJECTIVE Beta-thalassemia major (TM) is a genetic hemoglobin disorder causing chronic hemolytic anemia. Since cardiac insufficiency and arrhythmias are the primary causes of mortality in such patients, monitoring of cardiac iron load is important in management of the disorder. The purpose of this study was to investigate the importance of fragmented QRS (fQRS) and its relation to the cardiac T...

Sensitive profile searches and fold recognition were used to predict the structures of two yeast RNase P/MRP proteins. Rpp1p, which is one of the subunits common to eukaryotes and archaea, is predicted to adopt the seven-stranded TIM-barrel fold found in PHP phosphoesterases. Pop3p, initially thought to be one of the RNase P/MRP subunits unique to yeast, has been assigned the L7Ae/L30e fold. Th...

By using the apparatus (2) and medium (3) previously described, we have prepared two 4 to 5 liter batches of T2 bacteriophage by infection of the usual host, Escherichia coli, strain B. The raw titers were 1 and 3 X 1Ol2 infectious T2 particles per ml. Purification of these lysates by three or four cycles of deliberately wasteful differential centrifugation yielded some 1.5 to 2 gm. each of lyo...

Los Hongos Formadores de Micorrizas Arbusculares (HFMA) ayudan al intercambio y movilidad nutrientes asociarse con plantas, mejorando los cultivos. Por tanto, el objetivo fue evaluar HFMA en dos variedades caña azúcar para panela la localidad Suaita, Santander. Se estableció un diseño bloques azar, tres repeticiones cuatro tratamientos (T1: Acaulospora mellea, T2: Rhizoglomus irregulare, T3: Co...

AIM Cardiac magnetic resonance (CMR) can visualize inflammatory tissue changes in acute myocarditis. Several quantitative image-derived parameters have been described to enhance the diagnostic value of CMR, but no direct comparison of these techniques is available. METHODS AND RESULTS A total of 34 patients with suspected acute myocarditis and 50 control subjects underwent CMR. CMR protocol i...

BACKGROUND AND PURPOSE The detection of microbleeds differs strongly between studies, due to differences in scan protocol. This study aims to compare the visualization of microbleeds with 3D T2*-weighted imaging at 1.5T with 3D dual-echo T2*-weighted imaging at 7T. MATERIALS AND METHODS Thirty-four patients (29 male; mean age, 58 ± 12 years) with atherosclerotic disease from the Second Manife...

Effects of gastrocnemius glycogen (Gly) concentration on changes in transverse relaxation time (T2; ms) were studied after 5-min plantar flexion at 25% of maximum voluntary contraction (MVC). Gastrocnemius Gly, phosphorus metabolites, and T2 were measured in seven subjects by using interleaved 13C/31P magnetic resonance spectroscopy (MRS) at 4.7 T and magnetic resonance imaging (MRI; 1.5 T). Af...

The recovery process in sport plays an essential role in determining subsequent athletic performance. This study investigated the effectiveness of different recovery interventions after maximal exercise. Eighteen trained male cyclists initially undertook an incremental test to determine maximal oxygen consumption. The four recovery interventions tested were: passive, active (50% maximal oxygen ...