This research was conducted with the purpose of appraising the effect of Selenium (Se) and/or amino acid fertilizers (AA) on improving growth, physiology, and biofortification of parsley grown under high EC condition. Plants were foliarly supplemented with four levels of Se (0, 25, 50, 100 mgl-1) and/or two concentrations of AA (0 and 0.2%) three times with a week interval. The significantly in...

Gliding motility is critical for normal development of spore-filled fruiting bodies in the soil bacterium Myxococcus xanthus. Mutations in mgl block motility and development but one mgl allele can be suppressed by a mutation in masK, the last gene in an operon adjacent to the mgl operon. Deletion of the entire 5.5 kb masABK operon crippled gliding and fruiting body development and decreased spo...

Endocannabinoids function as retrograde messengers and modulate synaptic transmission through presynaptic cannabinoid CB1 receptors. The magnitude and time course of endocannabinoid signaling are thought to depend on the balance between the production and degradation of endocannabinoids. The major endocannabinoid 2-arachidonoylglycerol (2-AG) is hydrolyzed by monoacylglycerol lipase (MGL), whic...

We examine various versions of oriented cohomology and BorelMoore homology theories in algebraic geometry and put these two together in the setting of an “oriented duality theory”, a generalization of Bloch-Ogus twisted duality theory. We apply this to give a Borel-Moore homology version MGL ∗,∗ of Voevodsky’s MGL-theory, and a natural map θ : Ω∗ → MGL 2∗,∗ , where Ω∗ is the algebraic cobordism...

The endogenous cannabinoids (endocannabinoids) are lipid molecules that may mediate retrograde signaling at central synapses and other forms of short-range neuronal communication. The monoglyceride 2-arachidonoylglycerol (2-AG) meets several criteria of an endocannabinoid substance: (i) it activates cannabinoid receptors; (ii) it is produced by neurons in an activity-dependent manner; and (iii)...

Carbohydrate-protein interactions govern many crucial processes in biological systems including cell recognition events. We have used the sensitive force probe optical tweezers to quantify the interactions occurring between MGL lectins and MUC1 carrying the cancer-associated glycan antigens mucins Tn and STn. Unbinding forces of 7.6 pN and 7.1 pN were determined for the MUC1(Tn)-MGL and MUC1(ST...

Mg deficiency is considered as a risk factor of cardiovascular disorders like hypertension and atherosclerosis. MGH and MGL mice, selected for high and low Mg status, are animal models which present variations of Mg metabolism of genetic origin. The cardiovascular functions of these mice have never been studied. In this study, the arterial blood pressure of MGH and MGL strains was measured by p...

Dendritic cells (DCs) sense the microenvironment through several types of receptors recognizing pathogen-associated molecular patterns. In particular, C-type lectins, expressed by distinct subsets of DCs, recognize and internalize specific carbohydrate antigen in a Ca(2+) -dependent manner. Targeting of these receptors is becoming an efficient strategy of delivering antigens in DC-based antican...

The evolutionarily conserved lethal giant larvae (Lgl) tumor suppressor gene has an essential role in establishing apical-basal cell polarity, cell proliferation, differentiation, and tissue organization. However, the precise molecular mechanism by which the Lgl carries out its function remains obscure. In the current study, we have identified Ran-binding protein M (RanBPM) as a novel binding p...

Background & Aims of the Study: The objective of this study was to investigate the seed pre-treatment with salicylic acid (SA) on tolerance and remediation ability of Brassica oleracea var. acephala under lead and zinc stresses. Materials and Methods: Present study was conducted to evaluate phyto-accumulative ability of Brassica oleracea var. acephala in heavy metal concentrat...