This search involved synthesis of several new N-Substituted -3-chloro-
 2-azetidinones which were known as a high medicinal effectiveness for 2,
 4-Diamino-6-hydroxy pyrimidin in two steps. The first step included
 preparation Shiff bases (1-6) by condensation 2, 4-Diamino-6-hydroxy
 with many substituted aldehydes(4-hydroxy benzaldehyde, 2-
 bromobenzaldehyde, 4-dimeth...