Malignant germ cell tumor (GCT) formation is a well-known complication in the management of patients with a disorder of sex development (DSD). DSDs are defined as congenital conditions in which development of chromosomal, gonadal, or anatomical sex is atypical. DSD patients in whom the karyotype - at least at the gonadal level - contains (a part of) the Y chromosome are at increased risk for ne...

Rain drop size distributions (DSD) are measured with disdrometers at five different climatic locations in the Indian tropical region. The distribution of drop size is assumed to be lognormal to model the rain attenuation in the frequency range of 10–100 GHz. The rain attenuation is estimated assuming single scattering of spherical rain drops. Different attenuation characteristics are observed f...

A range of phenotypes that are associated with disorders of sex development (DSD) may also be encountered in patients with neurodevelopmental delay. In this study we have undertaken a collaborative retrospective review of anonymised phenotypic and genotypic data from the UK-wide Deciphering Developmental Disorders (DDD) study. Our objectives were to determine the frequency and range of DSD phen...

BACKGROUND Previous studies in quality of life (QOL) in individuals with disorders/differences of sex development (DSD) have been restricted to subpopulations of the condition. We describe QOL in adult persons with DSD compared to country specific references and assess the impact of diagnosis. METHODS The multicentre cross-sectional clinical evaluation (dsd-LIFE) took place in 14 specialized ...

Global software development generated a new era in software development by eliminating boundary of development team. Distributed software development has its own challenges and implementation of agile software development in it further brings the challenges due to their contradictory practices. In this paper we addressed the issues of DSD and proposed agile communication model for DSD. This mod...

Propagation of dust acoustic waves (DAWs) with the effect of power law dust size distribution (DSD) in a magnetized dusty plasma with opposite polarity dust is studied. Using a reductive perturbation method, a Zakharov-Kuznetsov equation appropriate for describing three-dimensional DAWs is derived. The compressive and rarefactive solitons are possible in the present model. Due to the DSD effect...

This study proposes investigation of new attenuation correction and microphysical retrieval methods for X-band polarimetric radar (XPOL). It will concentrate on exploring the dependence of the retrieval on raindrop size distribution variability, and its sensitivity with respect to the selection of oblateness-size relation (or axial ratio) and maximum diameter limit. Variations in the assumed fo...

Disorders of sex development (DSD) have long been documented in domestic animal species including horses. However, there is only a single report of an androgen receptor (AR) mutation causative of such a DSD syndrome in a horse pedigree. Here, we present a new familial AR mutation in horses. A missense mutation (c.2042G>C) at AR exon 4 explains the segregation of the DSD in a Thoroughbred horse ...

PURPOSE Peg-interferon (PegIFN)α2a or PegIFNα2b plus ribavirin (RBV) is the standard therapy for chronic hepatitis C virus (HCV) infection in Taiwan and Asia. It is commonly associated with adverse effects, but the issue of sexual and mental health is not well reported. This study aimed to evaluate the impact of anti-viral therapy with PegIFNα plus RBV on sexual desire and depression. METHODS...

Using a matrix of drop size distributions (DSDs), measured by a microscale array of disdrometers, a method of spatial and temporal DSD interpolation is presented. The goal of this interpolation technique is to estimate the DSD above the disdrometer array as a function of three spatial coordinates, time and drop diameter. This interpolation algorithm assumes simpliŽ ed drop dynamics, based on cl...