a box-behnken design with three replicates was used for preparation and evaluation of eudragit vancomycin (vcm) nanoparticles prepared by double emulsion. the purpose of this work was to optimize vcm nanoparticles to improve the physicochemical properties. nanoparticles were formed by using w1/o/w2 double-emulsion solvent evaporation method using eudragit rs as a retardant material. full factor...

Optimization of multi-criteria problems is a great need of producers to produce precision parts with low costs. Optimization of multi-performance characteristics is more complex compared to optimization of single-performance characteristics. The theory of grey system is a new technique for performing prediction, relational analysis, and decision making in many areas. In this paper, the use of g...

In machining industries, achieving better surface finish of a product is very essential. Surface finish is important in terms of tolerances, it reduces assembly time in mating surfaces which results in overall cost reduction. In this work, three cutting speeds, three feed rates and three depth of cuts were used in boring operation. During the boring operation, the accelerometer was fixed on the...

Internal Grinding is an approach to produce desired outcome with greater surface finish in metal cutting process. Unfortunately, external machining parameters play a vital role in research areas with numerous investigations. Considering this, present work focuses on the machining parameters on internal grinding process with necessary coolant oil as has been experimentally observed in our resear...

Tool wear increases cutting force, vibration, temperature, etc in end milling and reduces surface finish of the machined work piece. Mathematical model has been developed to predict the tool wear in terms of machining parameters such as helix angle of cutting tool, spindle speed, feed rate, axial and radial depth of cut. Central composite rotatable second order response surface methodology was ...

The wire electrical discharge machining (WEDM) experiments has been conducted using air and water mixture as a dielectric medium, is called environmental friendly near dry WEDM. In this technology, the dielectric fluid (Deionized water) is replaced by liquid-air to minimize the environmental impact in the machining zone and operator health. The effect of discharge current (I), Pulse width (TON)...

this study investigates removing ash and pyrite sulphur from bitumen by column flotation process. central composite design (ccd) of response surface methodology (rsm) was applied for modeling and optimization of the percentage of ash and pyrite sulphur removal from bitumen. the effects of five parameters namely the amounts of collector and frother agents, particle size, wash water rate and feed...

In the present study Response surface methodology (RSM) was used to investigate the combined effect of relevant process variables to maximize the production of xylanase in submerge fermentation by Penicillium citrinum MTCC 2553. The process variables include pH (6.5, 7.0, and 7.5); temperature (25, 30, and 35°C); agitation speed (190, 200, and 210 rpm); and, substrate (xylan) concentration (0.7...