a series of 42 pyrazolo[4,3-h]quinazoline-3-carboxamides as multi-cyclin-dependent kinaseinhibitors regarded as promising antitumor agents to complement the existing therapies, wassubjected to a three-dimensional quantitative activity relationship (3d qsar). different qsarmethods, comparative molecular field analysis (comfa), comfa region focusing, andcomparative molecular similarity indices an...

This paper examines procedural modeling as a tool for 3D modeling creation. Procedural modeling historically has been used for 3D visualization of natural features, but with the release of the software CityEngine in 2008, the technology can easily be adopted also in problem domains dealing with urban environments. Then, we will examine and compare two types of modeling, traditional and proc...

Dynamically stable biped robots mimicking human locomotion have received significant attention over the last few decades. Formerly, the existence of stable periodic gaits for straight walking of passive biped walkers was well known and investigated as the notion of passive dynamic walking. This study is aimed to elaborate this notion in the case of three dimensional (3D) walking and extend it f...

introduction: excessive temperature rise during drilling of the mandible for dental implant placement might damage adjacent osseous tissues. various factors affect temperature rise, including the geometrical parameters of surgical drills, one of which is the drill bit head angle. the aim of this research was to determine suitable drill bit head angle to induce minimum temperature rise during ma...

3D maps are one of the most attractive cartographical products for map users. They can present real environment in a photorealistic, readable way, keeping enough geo-spatial information needs different Very often users don’t make difference between and models environment. The aim this report is to clarify when we speak even discuss definition map.The article considers elements applied mapping w...

We present a new approach for accurate and fast reconstruction of 3D models from hand-drawn perspective sketches and imposed geometric constraints. A distinctive feature of the approach is the decomposition of the reconstruction process into the stages of correction of the 2D sketch and elevation of the 3D model. All 3D constraints that describe the spatial structure of the model are strictly s...