We report ROSAT X-ray observations of two powerful radio galaxies. 3C 280 provides evidence for a mixture of unresolved and extended emission, with the latter produced by hot plasma of insufficient pressure to confine the radio lobes and insufficient density for a cooling flow to have begun. 3C 220.3 gives only an X-ray upper limit, but one consistent with our interpretation of the X-ray emissi...

The aim of this study was to evaluate the association between thymidylate synthase (TS), methylenetetrahydrofolate reductase (MTHFR) and reduced folate carrier (SLC19A1) gene polymorphisms and the treatment efficacy of pemetrexed-based chemotherapy in advanced non-small cell lung cancer (NSCLC). Advanced NSCLC patients received pemetrexed and cisplatin every three weeks. Polymorphisms in the TS...

3C have a constant need to manage their own personal healthcare. This requires managing information related to their conditions. Given that the nature of healthcare is information intensive, effective management requires much more than simply providing patients with access to their electronic health record within a hospital-based system. This practice has been followed with little ongoing succe...

The two enteroviral proteinases, 2A proteinase (2A(pro)) and 3C proteinase (3C(pro)), induce host cell translation shutoff in enterovirus-infected cells by cleaving canonical translation initiation factors. Cleavage of poly(A)-binding protein (PABP) by 3C(pro) has been shown to be a necessary component for host translation shutoff. Here we show that 3C(pro) inhibits cap-independent translation ...

1. In this note we first generalize a result of P. R. Halmos [3] concerning commutators of (bounded ) operators on Hubert space. Then we obtain some partial results on a problem of commutators in von Neumann algebras which is closely related to another problem raised by Halmos in [4]. Let 3C be any (infinite-dimensional) Hubert space, and let £(3C) denote the algebra of all bounded operators on...

We present multi-frequency VLA observations of the two radio galaxies 3C 129 and 3C 129.1 embedded in a luminous X-ray cluster. These radio observations reveal a substantial difference in the Faraday Rotation Measures (RMs) toward 3C 129.1 at the cluster center and 3C 129 at the cluster periphery. After deriving the density profile from available X-ray data, we find that the RM structure of bot...

A thin, chemically inert 3C-SiC layer between GaN and Si helps not only to avoid the "melt-back" effect, but also to inhibit the crack generation in the grown GaN layers. The quality of GaN layer is heavily dependent on the unique properties of the available 3C-SiC/Si templates. In this paper, the parameters influencing the roughness, crystalline quality, and wafer bow are investigated and engi...

Zika virus (ZIKV) infections have been linked with neurological complications and congenital Zika syndrome. Given the high level of homology between ZIKV and the related flavivirus dengue virus (DENV), we investigated the level of cross-reactivity with ZIKV using a panel of DENV human mAbs. A majority of the mAbs showed binding to ZIKV virions, with several exhibiting neutralizing capacities ag...

The picornavirus 3C protease is required for the majority of proteolytic cleavages that occur during the viral life cycle. Comparisons of published amino acid sequences from 6 human rhinoviruses (HRV) and 20 human enteroviruses (HEV) show considerable variability in the 3C protease-coding region but strict conservation of the catalytic triad residues. Rupintrivir (formerly AG7088) is an irrever...

This study investigated the effect of Angelica sinensis polysaccharides (APS-3c) on rat osteoarthritis (OA) model in vivo and rat interleukin-1-beta- (IL-1 β -) stimulated chondrocytes in vitro. APS-3c was administrated into rat OA knee joints and had protective effects on rat OA cartilage in vivo. Primary rat articular chondrocytes were cotreated with APS-3c and IL-1 β   in vitro. 2~50  μ g/mL...