[1] Characterizing the hydration state of the forearc mantle wedge yields valuable information on frictional stability at the downdip edge of subduction megathrusts. Simultaneous inversion of Pand S-wave arrival times collected as part of the Costa Rica Seismogenic Zone Experiment yields 1D and 3D Pand S-wave velocity models (VP and VS) for the Nicoya Peninsula segment of the Middle America Tre...

BACKGROUND Insufficient data describe the relationship of hemodynamic parameters to left ventricular (LV) diastolic flow propagation velocity (Vp) measured using color M-mode Doppler echocardiography. METHODS An in vitro LV model used to simulate LV diastolic inflow with Vp measured under conditions of varying: 1) Stroke volume, 2) heart rate (HR), 3) LV volume, 4) LV compliance, and 5) trans...

Systemic hypoxia stimulates the release of vasopressin (VP) and adrenocorticotropin hormone (ACTH). To examine the involvement of catecholamine cell groups of the ventrolateral medulla (VLM) in the neuroendocrine responses, we have used the c-fos activity mapping technique to compare the effects of hypoxia on VLM catecholamine cells to those on neurosecretory VP and putative corticotropin relea...

We investigated the potential role of the 1-containing GABAA receptor in regulating the reinforcing properties of alcohol. To accomplish this, we developed 3-propoxy-carboline hydrochloride (3-PBC), a mixed agonist–antagonist benzodiazepine site ligand with binding selectivity at the 1 receptor. We then tested the capacity of 3-PBC to block alcohol-maintained responding in the ventral pallidum ...

Subcellular fractions of the bovine posterior pituitary, including one composed almost exclusively of pinched-off nerve endings (neurosecretosomes), were characterized electron microscopically, hormonally, and enzymically. 15% of the nerve terminals in the gland were isolated as neurosecretosomes, as estimated from determinations of lactic dehydrogenase, a soluble, cytoplasmic enzyme. Neurosecr...

The effects of microtubule inhibitors on cellular accumulation of 4'demethylepipodophyIlotoxin-9-(4,6-0-ethyIidine-/î-D-glucopyranoside) (VP-16) and subsequent epipodophyllotoxin-induced DNA single-strand breaks were investigated in human leukemia K562 cells. At concentra tions of 0.05-20 MM.vinblastine, vincristine, and maytansine similarly increased the steady-state cell concentration of VP-...

Nitric oxide (NO) synthase (NOS), the enzyme responsible for NO formation, is found in hypothalamic neurons containing oxytocin (OT), vasopressin (VP), and to a lesser extent corticotropin-releasing factor (CRF). Because NO is reported to modulate endocrine activity, we have investigated the hypothesis that endogenous NO participates in ACTH released by various secretagogues in the rat. In the ...

Central vasopressin (VP) release from magnocellular neuroendocrine cells (MNCs) in the supraoptic nucleus (SON) occurs from their somata and dendrites within the SON several hours after acute dehydration, and is an important autoregulatory mechanism influencing the systemic release of VP from MNC terminals in the posterior pituitary. To begin to explore the impact of polychlorinated biphenyls (...

In this paper, the structure of cocommutative vertex bialgebras is investigated. For a general bialgebra V, it proved that set G(V) group-like elements naturally an abelian semigroup, whereas P(V) primitive Lie algebra. g∈G(V), denote by Vg connected component containing g. Among main results, if V bialgebra, then V=⊕g∈G(V)Vg, where V1 subbialgebra which isomorphic to VP(V) associated algebra P...

The introduced method is a proposal for detecting spaces (links) and times (90 s periods) where the average speed below desirable, selecting vehicles in those so that are systematically gradually reduced from one simulation to another until we get presenting desirable all space time. With our can be detected specific enter street network on network’ links always greater than threshold. segment ...