School of Marilia, São Paulo, Brazil; Flow Citometry, and; Dermatology, Medical School of Marilia, Marilia, Brazil. Background: The prevalence of hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs) is high and its in vitro diagnostic is a challenge. The basophil activation test with determination by flow cytometry (FC), of the expression rate of CD63 molecules has been much studie...

Richard S. Gross (Jet Propulsion laboratory, California institute of Technology, 4800 Oak Grove Drive, Pasadena, CA 91 109; ph: 1-818-354-4010; fx: 1-818-393-6890; email: Richard [email protected]. gov) Yi Chao (Jet Propulsion Laboratory, California Institute of Teclmology, 4800 Oak Grove Drive, Pasadena, CA 91 109; ph: 1-818-354-8168; fx: 1-81 8-393-6720; email: [email protected]. gov) Steven L. ...

Glioblastoma multiforme is the most aggressive and common primary brain tumor, and is virtually incurable due to its therapeutic resistance to radiation and chemotherapy. Curcumin is a well-known phytochemical exhibiting antitumor activity on many human cancers including glioblastoma multiforme. Given the unique miRNA expression profiles in cancer cells compared to non-cancerous cells, we inves...

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Zadeh SS, Nabighadim A, Yasseri AM, Aghamir SM. The impact of socioeconomic status on prostate cancer screening and access to medical care. Family Medicine & Primary Care Review. 2022;24(4):375-378. doi:10.5114/fmpcr.2022.120863. APA Zadeh, S. S., Nabighadim, A., Yasseri, A. M., Aghamir, M. (2022). Review, 24(4), ...

STUDY OBJECTIVES To determine whether the polymorphic dinucleotide repeats found in intron 4 of the endothelial cell nitric oxide synthase (ecNOS) gene and the platelet GPIIIa PLA(1)/A(2) polymorphism are associated with myocardial infarction (MI) and venous thromboembolism (VTE) in African Americans. Because these two genes may interact physiologically, the third objective was to determine if ...

3 Testing Methods . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 370 3.1 General Principles in Testing Biodegradable Plastics . . . . . . . . . . . . . . 373 3.2 Analytical Procedures for Monitoring Biodegradation . . . . . . . . . . . . . . 375 3.2.1 Visual Observations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 375 3.2.2 Changes in Mechanical ...

Understanding the regulation of cardiac fibrosis is critical for controlling adverse cardiac remodeling during heart failure. Previously we identified miR-378 as a cardiomyocytes-abundant miRNA downregulated in several experimental models of cardiac hypertrophy and in patients with heart failure. To understand the consequence of miR-378 down-regulation during cardiac remodeling, our current stu...

The 4 -O-glucosides of 2 ,4,4 ,6 -tetrahydroxychalcone (THC) and 2 ,3,4,4 ,6 -pentahydroxychalcone (PHC) are present in the yellow snapdragon (Antirrhinum majus) flowers and serve as direct precursors for the synthesis of aurones, the yellow pigments of the flowers. Despite the metabolic significance of these chalcones in aurone biosynthesis, the biochemical properties of chalcone synthase (CHS...

Intestinal ischemia/reperfusion (I/R) injury remains a major clinical event and contributes to high morbidity and mortality rates, but the underlying mechanisms remain elusive. Recent studies have demonstrated that microRNAs (miRNAs) have important roles in organ I/R injury, but the changes and potential roles of miRNAs in intestinal I/R-induced intestinal injury are unclear. This study was des...