Genistein is a well known flavonoid that exhibits antioxidant, antiproliferative, proapoptotic, antiangiogenic, as well as estrogenic and anti-estrogenic activity. Extensive studies in the field of dermatology and cosmetology in recent years revealed that genistein is a promising anti-aging, anti-photoaging and anti-carcinogenic agent for skin care. Essential role in skin prematuring aging and ...

Dietary administration of the hepatocarcinogen 2-acetylaminofluorene (2-AAF) to rats results in the formation of a major hepatic DNA adduct, N-(deoxyguanosin-8-yl)-2-aminofluorene (dG-C8-AF). In liver DNA, dG-C8-AF reaches steady-state conditions after approximately 2 weeks of feeding and is removed in a biphasic manner. In these experiments, we have quantified adduct concentrations in a 370 ba...

The years since the introduction of System/360 in 1964 have produced very substantial changes in most aspects of the design, manufacture, and use of information-processing systems. The hardware technology for realizing logic fiinctions has evolved from semi-integrated circuit modules with single devices per chip to hundreds or thousands of circuits on a single silicon chip. The technology for h...

PURPOSE To analyze the surgical results in 370 patients who underwent enucleation or evisceration at our center, during a period of 11 years (1990-2000), determining the kind of correction used and the complications associated with the procedure. METHODS This was a retrospective study of medical records from all patients who underwent surgery by the same surgeon (FS) in the Oculoplastic Depar...

There is a large body of literature relating to computing system security that includes such issues as statements of problems and requirements for secure systems,'-' research in the design of secure computing efforts to develop techniques for verifying the correctness (and hence impenetrability) of prog r a m ~ , ~ and reports of organized efforts to determine the penetrability of various o...

BACKGROUND Effects of high iodine-concentration contrast material on the image quality of coronary CT angiography (CCTA) have not been well evaluated. PURPOSE To compare the image quality and attenuation values of CCTA between patients administered iopromide 370 and iomeprol 400 with the use of 64-slice multidetector CT. MATERIAL AND METHODS Patients were prospectively enrolled and were ran...

by blocking H /K -ATPase at the terminal steps of gastric acid secretion process. So, PPIs are assumed that their potency of gastric antisecretory effect is stronger than that of the histamine H2-receptor antagonists. Omeprazole, one of the PPIs, was discovered by Fellenius et al. and is widely used in treatment of peptic ulcer, gastro esophageal reflux disease and eradication of Helicobacter p...

Memory consistency models are notorious for being difficult to define precisely, to reason about, and to verify. More than a decade of effort has gone into nailing down the definitions of the ARM and IBM Power memory models, and yet there still remain aspects of those models which (perhaps surprisingly) remain unresolved to this day. In response to these complexities, there has been somewhat of...

Dbx is the standard source-level debugger on most Unix1 workstations. Over the past six years Dbx has grown from a debugger for interpreted Pascal programs to a debugger for compiled C, C++, FORTRAN, Pascal, and Modula-2 programs. Dbx also has been retargetted to a variety of architectures, including VAX2, Motorola 680003, MIPS, IBM RT-PC4, IBM 370, Sun SPARC, and Intel 80386. This paper descri...

BACKGROUND AND PURPOSE Leisure-time physical activity protects from stroke. It is insufficiently established whether early lifetime physical activity is independently protective and whether some etiologic stroke subgroups particularly benefit from physical activity. We tested the hypothesis that both recent and early-adulthood sports activities are associated with reduced odds of stroke and ana...