Transmembrane helix seven residues of G protein-coupled receptors (GPCRs) couple agonist binding to a conserved receptor activation mechanism. Amino-terminal residues of the GnRH peptide determine agonist activity. We investigated GnRH interactions with the His(7.36(305)) residue of the GnRH receptor, using functional and computational analysis of modified GnRH receptors and peptides. Non-polar...

OBJECTIVES To evaluate the positivity of Phadiatop in children from several Brazilian pediatric allergology centers and to compare its results with the presence of serum specific IgE to inhalant and food allergens. PATIENTS AND METHOD Phadiatop and serum specific IgE levels (RAST) to inhalant and food allergens (UniCAP - Pharmacia) were measured in 457 children from several pediatric allergy ...

Lactation records are calculated from data on milk, fat, and protein obtained from one or more milkings on several days during the lactation. The test interval method, which estimated missing daily milk yields by simple interpolation, was used for many years for standard monthly data but may not be as useful for the wider variety of test plans now being proposed. More accurate 305-d yields can ...

Corresponding Author: R. Graham Barr, MD, DrPH 622 W 168th Street, PB 9 East, Room 105 New York, NY 10032 Phone: 212-305-4895 Fax: 212-305-9349 [email protected].

Calving records from the Animal Breeding Center of Iran collected from January 1993 to December 2007 and comprising 1 163 594 Holstein calving events from 2 552 herds were used to evaluate reported perinatal calf mortality, 305-d milk yield, 305-d fat yield of milk and 305-d fat percentage of milk in singleand twin-births. A logistic regression model was constructed to analyze calf mortality be...

In this lecture we be begin our tour of discrete mathematics and algorithms by looking at one of the most fundamental and classic problems in combinatorial optimization and graph theory, computing the edge connectivity of an undirected, unweighted graph. In the next few lectures we will take a more principled and fundamental approach to graph theory and connectivity. The goal of today is to get...