Several mechanisms have been proposed to explain the pathogenesis of severe congenital neutropenia (SCN); however, the mechanism(s) still remains unknown. In particular, clinical observations suggest that abnormal responsiveness of myeloid progenitors to hematopoietic growth factors (HGFs) is a possible mechanism. Therefore, to better define the status of hematopoietic progenitors in the bone m...

Anionic poly(vinylcaprolactam-co-itaconicacid-co-dimethylitaconate) microgels were synthesized via dispersion polymerization and their responsiveness towards cations, namely Mg2+, Sr2+, Cu2+ Fe3+, was investigated.

clinical asthma and airway responsiveness appear to be less severe when diabetes is superimposed. the aim of the present study was to determine the possible role of nitric oxide (no) in the airway reactivity under diabetic and diabetic-allergic conditions. twenty-five male guinea-pigs were divided into five groups of five each as follows: diabetic, antigen sensitized, diabetic- antigen sensitiz...

conclusions these results showed the preventive effect of hydroethanolic extract of n. sativa on tracheal responsiveness of guinea pig model of copd, which was as effective as vitamin c. results the tracheal responsiveness to both methacholine and ovalbumin in guinea pigs with copd were significantly higher than those of controls (p < 0.001 for both cases). the tracheal responsiveness in the co...

Little is known about how fathers’ food parenting practices (FPP) are linked with children’s eating behaviors and whether these associations differ from mothers. This study examined between paternal maternal FPP among children aged 5–12 years. A sample of 565 parents (53% fathers) completed: 1) the item bank, which measured 11 constructs three domains (control, autonomy promotion, structure) 2)...

background considering patients’ needs and expectations in the process of healthcare delivery improves the quality of services. this study aimed to investigate the responsiveness of general public and private hospitals in mashhad, iran.   methods in this cross-sectional and explanatory study, hospitalized patients (with at least 2 days of stay) in general private and public hospitals in mashhad...

In contemporary clinical practice and research, many different instruments are used to measure depression severity. Santor et al. [1] identified no fewer than 280 scales developed in the last century, many of which are still in use. The responsiveness of these various depression scales to treatmentdand the comparison of responsiveness among scalesdhas become an important research topic. Respons...

BACKGROUND Many patients with chronic obstructive lung disease show increased airways responsiveness to histamine. We investigated the hypothesis that increased airways responsiveness predicts the development and remission of chronic respiratory symptoms. METHODS We used data from 24-year follow-up (1965-90) of 2684 participants in a cohort study in Vlagtwedde and Vlaardingen, Netherlands. In...

BACKGROUND The aim of this study was to examine the impact of intravenous methylprednisolone therapy (IVMP) on the recovery of walking ability in patients experiencing multiple sclerosis (MS) relapses, to compare the responsiveness of walking-based measures, and to estimate the impact of different walking-based measures responsiveness on clinical trials. MATERIAL/METHODS The study included 49...